Factors Associated with Maternal-Child Transmission of HIV-1 in Southeastern Brazil: A Retrospective Study

Factors Associated with Maternal-Child Transmission of HIV-1 in Southeastern Brazil: A... Mother-to-child transmission (MTCT) is the main mode of HIV-1 acquisition among young children worldwide. The goals of this study were to estimate the proportion of HIV MTCT and to identify factors associated with transmission. We reviewed data for HIV-infected pregnant women that had been reported to the National Information on Reportable Diseases System (SINAN) in Espírito Santo state, Brazil, between January 2007 and December 2012. HIV cases in children were followed until age 18 months. The proportion of women who transmitted HIV to their babies was 14% (95% CI 11–17%). In a multivariate logistic regression model, pregnant women who had lower than primary school education (OR 2.74; 95% CI 1.31–5.71), had 2 or more pregnancies during the study period (OR 2.28; 95% CI 1.07–4.84), had emergency cesarean delivery (OR 4.32; 95% CI 1.57–11.9), and did not receive antiretroviral therapy during prenatal care (OR 2.41; 95% CI 1.09–5.31) had higher odds of HIV MTCT. Effort should be made to encourage health care workers and pregnant women to use services for the prevention of MTCT. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AIDS and Behavior Springer Journals

Factors Associated with Maternal-Child Transmission of HIV-1 in Southeastern Brazil: A Retrospective Study

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Public Health; Health Psychology; Infectious Diseases
ISSN
1090-7165
eISSN
1573-3254
D.O.I.
10.1007/s10461-018-2172-8
Publisher site
See Article on Publisher Site

Abstract

Mother-to-child transmission (MTCT) is the main mode of HIV-1 acquisition among young children worldwide. The goals of this study were to estimate the proportion of HIV MTCT and to identify factors associated with transmission. We reviewed data for HIV-infected pregnant women that had been reported to the National Information on Reportable Diseases System (SINAN) in Espírito Santo state, Brazil, between January 2007 and December 2012. HIV cases in children were followed until age 18 months. The proportion of women who transmitted HIV to their babies was 14% (95% CI 11–17%). In a multivariate logistic regression model, pregnant women who had lower than primary school education (OR 2.74; 95% CI 1.31–5.71), had 2 or more pregnancies during the study period (OR 2.28; 95% CI 1.07–4.84), had emergency cesarean delivery (OR 4.32; 95% CI 1.57–11.9), and did not receive antiretroviral therapy during prenatal care (OR 2.41; 95% CI 1.09–5.31) had higher odds of HIV MTCT. Effort should be made to encourage health care workers and pregnant women to use services for the prevention of MTCT.

Journal

AIDS and BehaviorSpringer Journals

Published: May 29, 2018

References

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