Eur J Nucl Med Mol Imaging (2017) 44:1779–1780 DOI 10.1007/s00259-017-3738-9 IMAGE OF THE MONTH 1 1 1 1 Madhavi Tripathi & Abhinav Bansal & Vivek Baghel & Praveen Kumar & Chandrasekhar Bal Received: 8 April 2017 /Accepted: 19 May 2017 /Published online: 6 June 2017 Springer-Verlag Berlin Heidelberg 2017 A 58-year-old female presented with insidious onset progres- associated with AD pathology but other pathologies like sive vision and visuospatial difficulties followed by memory Lewy bodies have also been identified on histopatholgy and sleep problems for 3 years. With a clinical diagnosis of . It affects the occipital, parietal and occipitotemporal posterior cortical atrophy-variant of Alzheimers disease (AD) cortices resulting in visuospatial and visuopercetive def- or Diffuse Lewy body dementia, she was referred for F-18 icits . Recent advances in selective tau tracer devel- Fluorodeoxyglucose (FDG) and F-18 Tau (Tau-AD-ML104, opment for PET imaging have allowed in vivo explora- ORA) positron emission tomography (PET) which revealed tion of the presence and extent of tau pathology [4, 5]. hypometabolism (upper row) in the parietal, and posterior Taudepositionin vivointhiscaseprovidesdirectevi- temporo-occipital cortices (more severe in the right cerebral dence for the presence of Alzheimers pathology. In ad- hemisphere) with abnormal Tau binding in
European Journal of Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Jun 6, 2017
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