Extravasation of clarithromycin

Extravasation of clarithromycin Eur J Plast Surg (1998) 21:160±161  Springer-Verlag 1998 LETTER T O T HE EDITOR G. OToole ´ E. Eltigani ´ H. Henderson Received: 20 May 1997 / Accepted: 5 August 1997 Sir: To our knowledge, severe injury from extravasated clari- thromycin has not been reported in the literature. We were recently referred an 18-year-old man with such an injury. The clarithromycin had been administered incorrectly, as a concentrated solution (500 mg in 10 ml of saline), too rapidly and through a vein in the dorsum of the hand. It should be given in dilute solution (500 mg in 250 ml of saline), over 60 min, through a proximal vein [1]. During its administration, the patient complained of severe pain, which was diagnosed wrongly as phlebitis. Gradually the hand become increasingly swollen and ischaemic, and the diagnosis became clear (Figs. 1±3). The patient was re- ferred to our unit, 12 h after the injury. Since extravasa- tion is a common complication of intravenous therapy [2, 3], it is surprising that there is no certainty of the best Fig. 1 Dorsum of the hand 12 h after extravasation of clarithromy- cin G. OToole ( ) ´ E. Eltigani ´ H. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Extravasation of clarithromycin

Loading next page...
Copyright © 1998 by Springer-Verlag Berlin Heidelberg
Medicine & Public Health; Plastic Surgery
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial