Extracellular Vesicles: Biomarkers, Therapeutics, and Vehicles in the Visual System

Extracellular Vesicles: Biomarkers, Therapeutics, and Vehicles in the Visual System Curr Ophthalmol Rep (2017) 5:276–282 DOI 10.1007/s40135-017-0153-0 REGENERATIVE MEDICINE IN OPHTHALMOLOGY (D MYUNG, SECTION EDITOR) Extracellular Vesicles: Biomarkers, Therapeutics, and Vehicles in the Visual System 1,2,3 2,3,4 Yolandi van der Merwe & Michael B. Steketee Published online: 6 October 2017 Springer Science+Business Media, LLC 2017 Abstract how heterogeneous EV populations modulate positive tissue Purpose We discuss recent advances in extracellular vesicle remodeling. (EV) technology as biomarkers, therapeutics, and drug deliv- ery vehicles in the visual system with an emphasis on the . . . Keywords Extracellular vesicles Exosomes Biomarkers retina. . . . Retina Optic nerve Retinal ganglion cell miRNA Recent Findings Retinal cell-type specific EVs can be detect- ed in the blood and in the aqueous humor and EV miRNA cargoes can be used diagnostically to predict retinal disease progression. Studies have now shown EVs can deliver bioac- Introduction tive miRNA and AAV cargoes to the inner retinal cell layers and, in some models, improve retinal ganglion cell (RGC) Extracellular vesicles (EVs) are increasingly appreciated as survival and axon regeneration. important factors regulating intercellular communication in Summary EV molecular profiles and cargoes are attractive the visual system and are now being explored as biomarkers, biomarkers for retinal and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Ophthalmology Reports Springer Journals

Extracellular Vesicles: Biomarkers, Therapeutics, and Vehicles in the Visual System

Loading next page...
 
/lp/springer_journal/extracellular-vesicles-biomarkers-therapeutics-and-vehicles-in-the-YWAyddRXUn
Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Ophthalmology
eISSN
2167-4868
D.O.I.
10.1007/s40135-017-0153-0
Publisher site
See Article on Publisher Site

Abstract

Curr Ophthalmol Rep (2017) 5:276–282 DOI 10.1007/s40135-017-0153-0 REGENERATIVE MEDICINE IN OPHTHALMOLOGY (D MYUNG, SECTION EDITOR) Extracellular Vesicles: Biomarkers, Therapeutics, and Vehicles in the Visual System 1,2,3 2,3,4 Yolandi van der Merwe & Michael B. Steketee Published online: 6 October 2017 Springer Science+Business Media, LLC 2017 Abstract how heterogeneous EV populations modulate positive tissue Purpose We discuss recent advances in extracellular vesicle remodeling. (EV) technology as biomarkers, therapeutics, and drug deliv- ery vehicles in the visual system with an emphasis on the . . . Keywords Extracellular vesicles Exosomes Biomarkers retina. . . . Retina Optic nerve Retinal ganglion cell miRNA Recent Findings Retinal cell-type specific EVs can be detect- ed in the blood and in the aqueous humor and EV miRNA cargoes can be used diagnostically to predict retinal disease progression. Studies have now shown EVs can deliver bioac- Introduction tive miRNA and AAV cargoes to the inner retinal cell layers and, in some models, improve retinal ganglion cell (RGC) Extracellular vesicles (EVs) are increasingly appreciated as survival and axon regeneration. important factors regulating intercellular communication in Summary EV molecular profiles and cargoes are attractive the visual system and are now being explored as biomarkers, biomarkers for retinal and

Journal

Current Ophthalmology ReportsSpringer Journals

Published: Oct 6, 2017

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off