Digestive Diseases and Sciences (2018) 63:2810–2812 https://doi.org/10.1007/s10620-018-5147-8 C ASE REPOR T Extensive Gastrointestinal Manifestations as the Main Relapsing Disease in Granulomatosis with Polyangiitis 1 2 3 1 Omar Vergara‑Fernández · Fredy Chablé‑Montero · Natllely Ruiz · David Mitre‑Reyes · 4 5 3 3,6 Eduardo Cerda‑Contreras · Andrea Hernández · Erika Marroquín‑Fabián · Luis Felipe Flores‑Suárez Received: 15 October 2017 / Accepted: 28 May 2018 / Published online: 4 June 2018 © Springer Science+Business Media, LLC, part of Springer Nature 2018 Keywords Granulomatosis with polyangiitis · ANCA · Vasculitis · Gastrointestinal · Anorectal Granulomatosis with polyangiitis (GPA-Wegener’s) is (nodular disease, biopsy-proven), was treated with glucocor- a small vessel vasculitis associated with the presence of ticoids (GC) and methotrexate (MTX) as remission induc- antineutrophil cytoplasm autoantibodies. Gastrointestinal tion therapy, followed by MTX as maintenance treatment for involvement ranges from 5 to 20% of cases. We describe a 5 years. After remission was achieved at month 6, gradual case in whom relapsing disease with widespread gastrointes- tapering of MTX during the following 4.5 years allowed for tinal manifestations including pharyngeal, esophageal, small its withdrawal in 2010. He already had a history of a hemor- and large intestine, and anus was present for the first time. rhoidal disease, leading in 2013 to ferropenic anemia, which A 43-years-old male, with a 10-year history
Digestive Diseases and Sciences – Springer Journals
Published: Jun 4, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera