Expression of caveolin-1 in breast cancer stroma as apotential prognostic biomarker of survival andprogression: ameta-analysis

Expression of caveolin-1 in breast cancer stroma as apotential prognostic biomarker of survival... original article Wien Klin Wochenschr (2017) 129:558–563 DOI 10.1007/s00508-017-1173-3 Expression of caveolin-1 in breast cancer stroma as a potential prognostic biomarker of survival and progression: a meta-analysis Xiuying Li · Jinfan Sun · Shuenqin Hu Received: 19 May 2016 / Accepted: 25 January 2017 / Published online: 31 March 2017 © Springer-Verlag Wien 2017 Summary fibroblasts was a significant predictor of DFS/PFS Background It has been shown that caveolin-1 (HR = 2.79, 95% CI: 1.75–4.46). plays a potential role as a diagnostic and prognos- Conclusion Our results indicated that lack of expres- tic biomarker in various cancer types. The aim of sion of caveolin-1 in the breast cancer stroma is asso- the present study was to clarify whether caveolin- ciated with a poor prognosis. 1 expressed in the breast cancer stroma could be a prognostic factor for breast cancer patients. Keywords Caveolin-1 · Tumor stroma · Cancer-asso- Methods We searched the PubMed, ScienceDirect and ciated fibroblasts · Breast cancer · Meta-analysis Web of Science databases for published literature in- vestigating associations between stromal caveolin-1 Introduction expression and survival outcome in breast cancer pa- tients. With respect to survival outcomes, the pooled Breast cancer is the most common form of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Wiener klinische Wochenschrift Springer Journals

Expression of caveolin-1 in breast cancer stroma as apotential prognostic biomarker of survival andprogression: ameta-analysis

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Publisher
Springer Vienna
Copyright
Copyright © 2017 by Springer-Verlag Wien
Subject
Medicine & Public Health; Medicine/Public Health, general; Internal Medicine; Endocrinology; Gastroenterology; Pneumology/Respiratory System
ISSN
0043-5325
eISSN
1613-7671
D.O.I.
10.1007/s00508-017-1173-3
Publisher site
See Article on Publisher Site

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