Expression and mapping of the mouse S7/Pmsc2 gene, homolog of an essential mitotic gene in yeast

Expression and mapping of the mouse S7/Pmsc2 gene, homolog of an essential mitotic gene in yeast Mammalian Genome 8, 352-354 (1997). 9 Spnnger-Verlag New York Inc. 1997 Expression and mapping of the mouse S71Pmsc2 gene, homolog of an essential mitotic gene in yeast Jeremy Allen,* Laurence Colleaux,** Duncan Davidson, Elisabeth Graham, Muriel Lee, Robert Hill, Cathy Abbott,*** Colin Gordon MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland, UK Received: 13 August 1996 / Accepted: 23 December 1996 Polyubiquitinated proteins are degraded by a 26S ATP-dependent stricted distally (Fig. 1B,C). The highest levels are detected in the protease. This large complex contains a proteolytic core, previ- mesenchymal cells at the distal rim of the bud under the apical ously identified as the 20S proteasome, which associates with ectodermal ridge (AER) corresponding to the progress zone. No regulatory components to form the 26S particle (reviewed by Rech- strong hybridization signal is present in the AER itself (Fig. 1D). steiner et al. 1993; Hershko and Ciechanover 1992). Recent studies In E12.5 embryos (Fig. 1E), Pmsc2 is expressed in the mesen- in yeast show that mutations in two of the regulatory components, chyme lining the digits but not throughout the whole of the inter- $4 and $7, interrupt mitosis, indicating a role for the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Expression and mapping of the mouse S7/Pmsc2 gene, homolog of an essential mitotic gene in yeast

Loading next page...
 
/lp/springer_journal/expression-and-mapping-of-the-mouse-s7-pmsc2-gene-homolog-of-an-Eq9LLjxjLx
Publisher
Springer-Verlag
Copyright
Copyright © 1997 by Springer-Verlag
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900439
Publisher site
See Article on Publisher Site

Abstract

Mammalian Genome 8, 352-354 (1997). 9 Spnnger-Verlag New York Inc. 1997 Expression and mapping of the mouse S71Pmsc2 gene, homolog of an essential mitotic gene in yeast Jeremy Allen,* Laurence Colleaux,** Duncan Davidson, Elisabeth Graham, Muriel Lee, Robert Hill, Cathy Abbott,*** Colin Gordon MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland, UK Received: 13 August 1996 / Accepted: 23 December 1996 Polyubiquitinated proteins are degraded by a 26S ATP-dependent stricted distally (Fig. 1B,C). The highest levels are detected in the protease. This large complex contains a proteolytic core, previ- mesenchymal cells at the distal rim of the bud under the apical ously identified as the 20S proteasome, which associates with ectodermal ridge (AER) corresponding to the progress zone. No regulatory components to form the 26S particle (reviewed by Rech- strong hybridization signal is present in the AER itself (Fig. 1D). steiner et al. 1993; Hershko and Ciechanover 1992). Recent studies In E12.5 embryos (Fig. 1E), Pmsc2 is expressed in the mesen- in yeast show that mutations in two of the regulatory components, chyme lining the digits but not throughout the whole of the inter- $4 and $7, interrupt mitosis, indicating a role for the

Journal

Mammalian GenomeSpringer Journals

Published: Mar 21, 2009

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off