Mammalian Genome 11, 930–933 (2000). DOI: 10.1007/s003350010162 Incorporating Mouse Genome © Springer-Verlag New York Inc. 2000 Expression analysis and mapping of the mouse and human transcriptional regulator CA150 1, 2 1 1, 2 2 * ** Jens Bohne, Susan E. Cole, Carlos Sun ˜e, Brian R. Lindman, Victor D. Ko, Thomas F. Vogt, 1,3 Mariano A. Garcia-Blanco Department of Genetics, 424 CARL Building, Duke University Medical Center, Durham, North Carolina 27710, USA Department of Molecular Biology, Lewis Thomas Laboratory 147, Washington Road, Princeton University, Princeton, New Jersey 08540, USA Departments of Microbiology and Medicine, 424 CARL Building, Duke University Medical Center, Durham, North Carolina 27710, USA Received: 15 February 2000 / Accepted: 18 May 2000 The coactivator of 150 kDa (CA150) was purified and cloned sequence. The predicted 1079 amino acid protein of mouse CA150 following activities that regulate transcription from the HIV-1 pro- is 97.6% identical at the protein level and 90% identical at the moter (Sun ˜ e and Garcia-Blanco 1995; Sun ˜ e et al. 1997). CA150 nucleic acid level to human CA150, suggesting the genes are or- affects transcription of the HIV-1 LTR and of the a4 integrin thologs (Fig. 1A). Very recently, two mouse
Mammalian Genome – Springer Journals
Published: Feb 27, 2014
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