Mammalian Genome 8, 859-862 (1997). ~Cv ellOme 9 Sprmger-Verlag New York Inc. 1997 Expressed sequences within pericentromeric heterochromatin of human Chromosome 22 Nikolaus Blin, 1 Michael Scholz, 2 Bernd Wissinger, 3 Roman Miillenbach, 4 Carsten Pusch 1 ~Institute of Anthropology and Human Genetics, Dept. of Molecular Genetics, University of Tuebingen, Wilhelmstr 27, 72074 Tuebingen, Germany 2Institute of Prehistoric Research, Dept. of Archaeobiology, University of Tuebingen, Eugenstrasse 40, 72072 Tuebingen, Germany 3Universit~itsaugenklinik Abteilung II, Molekulargenetisches Labor, Auf der Morgenstelle 15, 72076 Tuebingen, Germany 4Institute of Child Health, Haematology and Oncology, Imperial Cancer Research Fund, London WC1N1EH, UK Received: 22 April 1997 / Accepted: 14 July 1997 In addition to the classic, protein-encoding sequences found in the five clones (COS 1, 4, 5, 7, and 8) contained overlapping regions genomes of higher-order cells, numerous sequence fragments with within two contigs. Southern filters were subsequently hybridized repetitive motifs are known. Their irregular distribution throughout to sonicated human placental DNA, p22hom48.4 (D22Z3; the genome and the fact that their contribution to the performance Metzdorf et al. 1988), p22/1 (D22Z2; McDermid et al. 1986), of genetic functions is largely unknown have resulted in the un- 13-satellite repeats (pJOG6; Assum et al. 1993), 18S- and
Mammalian Genome – Springer Journals
Published: Mar 24, 2009
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