Exposure to Secondhand Smoke Impairs Fracture Healing in Rats

Exposure to Secondhand Smoke Impairs Fracture Healing in Rats Clinical Orthopaedics Clin Orthop Relat Res (2017) 475:894–902 ® and Related Research DOI 10.1007/s11999-016-5184-6 A Publication of The Association of Bone and Joint Surgeons® BASIC RESEARCH Hildemberg A. R. Santiago PhD, Ariane Zamarioli PhD, Manoel D. Sousa Neto PhD, Jose B. Volpon MD, PhD Received: 29 June 2016 / Accepted: 18 November 2016 / Published online: 30 November 2016 The Association of Bone and Joint Surgeons1 2016 Abstract secondhand exposure to tobacco smoke adversely affects Background Nonsmokers may be affected by environ- fracture healing. mental tobacco smoke (secondhand smoke), but the effects Methods A mid-diaphyseal fracture was created in the of such exposure on fracture healing have not been well femur of 41 female Wistar rats and fixed with an intra- studied. medullary metallic pin; 14 rats were excluded (nine for Questions/purposes To explore the possible effects of inadequate fractures and five for K wire extrusion). passive inhalation of tobacco smoke on the healing of a Tobacco exposure was provided by a smoking machine on diaphyseal fracture in femurs of rats. We hypothesized that a daily basis of four cigarettes a day. Each cigarette yielded 10 mg tar and 0.8 mg nicotine, and was puffed by alter- nating injections http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Orthopaedics and Related Research Springer Journals

Exposure to Secondhand Smoke Impairs Fracture Healing in Rats

Loading next page...
 
/lp/springer_journal/exposure-to-secondhand-smoke-impairs-fracture-healing-in-rats-30PqG4WkCY
Publisher
Springer US
Copyright
Copyright © 2016 by The Association of Bone and Joint Surgeons®
Subject
Medicine & Public Health; Orthopedics; Surgical Orthopedics; Medicine/Public Health, general; Surgery; Sports Medicine; Conservative Orthopedics
ISSN
0009-921X
eISSN
1528-1132
D.O.I.
10.1007/s11999-016-5184-6
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial