Exposure to Secondhand Smoke Impairs Fracture Healing in Rats

Exposure to Secondhand Smoke Impairs Fracture Healing in Rats Clinical Orthopaedics Clin Orthop Relat Res (2017) 475:894–902 ® and Related Research DOI 10.1007/s11999-016-5184-6 A Publication of The Association of Bone and Joint Surgeons® BASIC RESEARCH Hildemberg A. R. Santiago PhD, Ariane Zamarioli PhD, Manoel D. Sousa Neto PhD, Jose B. Volpon MD, PhD Received: 29 June 2016 / Accepted: 18 November 2016 / Published online: 30 November 2016 The Association of Bone and Joint Surgeons1 2016 Abstract secondhand exposure to tobacco smoke adversely affects Background Nonsmokers may be affected by environ- fracture healing. mental tobacco smoke (secondhand smoke), but the effects Methods A mid-diaphyseal fracture was created in the of such exposure on fracture healing have not been well femur of 41 female Wistar rats and fixed with an intra- studied. medullary metallic pin; 14 rats were excluded (nine for Questions/purposes To explore the possible effects of inadequate fractures and five for K wire extrusion). passive inhalation of tobacco smoke on the healing of a Tobacco exposure was provided by a smoking machine on diaphyseal fracture in femurs of rats. We hypothesized that a daily basis of four cigarettes a day. Each cigarette yielded 10 mg tar and 0.8 mg nicotine, and was puffed by alter- nating injections http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Orthopaedics and Related Research Wolters Kluwer Health

Exposure to Secondhand Smoke Impairs Fracture Healing in Rats

Loading next page...
 
/lp/springer_journal/exposure-to-secondhand-smoke-impairs-fracture-healing-in-rats-30PqG4WkCY
Publisher
Springer US
Copyright
Copyright © 2016 by The Association of Bone and Joint Surgeons®
Subject
Medicine & Public Health; Orthopedics; Surgical Orthopedics; Medicine/Public Health, general; Surgery; Sports Medicine; Conservative Orthopedics
ISSN
0009-921X
eISSN
1528-1132
D.O.I.
10.1007/s11999-016-5184-6
Publisher site
See Article on Publisher Site

Abstract

Clinical Orthopaedics Clin Orthop Relat Res (2017) 475:894–902 ® and Related Research DOI 10.1007/s11999-016-5184-6 A Publication of The Association of Bone and Joint Surgeons® BASIC RESEARCH Hildemberg A. R. Santiago PhD, Ariane Zamarioli PhD, Manoel D. Sousa Neto PhD, Jose B. Volpon MD, PhD Received: 29 June 2016 / Accepted: 18 November 2016 / Published online: 30 November 2016 The Association of Bone and Joint Surgeons1 2016 Abstract secondhand exposure to tobacco smoke adversely affects Background Nonsmokers may be affected by environ- fracture healing. mental tobacco smoke (secondhand smoke), but the effects Methods A mid-diaphyseal fracture was created in the of such exposure on fracture healing have not been well femur of 41 female Wistar rats and fixed with an intra- studied. medullary metallic pin; 14 rats were excluded (nine for Questions/purposes To explore the possible effects of inadequate fractures and five for K wire extrusion). passive inhalation of tobacco smoke on the healing of a Tobacco exposure was provided by a smoking machine on diaphyseal fracture in femurs of rats. We hypothesized that a daily basis of four cigarettes a day. Each cigarette yielded 10 mg tar and 0.8 mg nicotine, and was puffed by alter- nating injections

Journal

Clinical Orthopaedics and Related ResearchWolters Kluwer Health

Published: Nov 30, 2016

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off