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H. Bourhy, P. Rollin, J. Vincent, P. Sureau (1989)
Comparative field evaluation of the fluorescent-antibody test, virus isolation from tissue culture, and enzyme immunodiagnosis for rapid laboratory diagnosis of rabiesJournal of Clinical Microbiology, 27
(1996)
The behavior of bats Pipistrellus pipistrellus after experimental inoculation with rabies and rabies-like viruses and some aspects of pathogenesis
Á. Setién, B. Brochier, N. Tordo, O. Paz, P. Desmettre, D. Peharpre, P. Pastoret (1998)
Experimental rabies infection and oral vaccination in vampire bats (Desmodus rotundus).Vaccine, 16 11-12
S. Morse (1994)
The Evolutionary biology of viruses
Constantine Dg (1966)
Transmission experiments with bat rabies isolates: reaction of certain Carnivora, opossum, and bats to intramuscular inoculations of rabies virus isolated from free-tailed bats.American Journal of Veterinary Research, 27
Gareth Hughes, Jean Smith, C. Hanlon, Charles Rupprecht (2004)
Evaluation of a TaqMan PCR Assay To Detect Rabies Virus RNA: Influence of Sequence Variation and Application to Quantification of Viral LoadsJournal of Clinical Microbiology, 42
I. Kuzmin, G. Hughes, A. Botvinkin, L. Orciari, C. Rupprecht (2005)
Phylogenetic relationships of Irkut and West Caucasian bat viruses within the Lyssavirus genus and suggested quantitative criteria based on the N gene sequence for lyssavirus genotype definition.Virus research, 111 1
H. Badrane, C. Bahloul, Pierre Perrin, N. Tordo (2001)
Evidence of Two Lyssavirus Phylogroups with Distinct Pathogenicity and ImmunogenicityJournal of Virology, 75
B. Kissi, H. Badrane, L. Audry, A. Lavenu, Noël Tordo, M. Brahimi, H. Bourhy (1999)
Dynamics of rabies virus quasispecies during serial passages in heterologous hosts.The Journal of general virology, 80 ( Pt 8)
S. Sulkin, P. Krutzsch, R. Allen, C. Wallis (1959)
STUDIES ON THE PATHOGENESIS OF RABIES IN INSECTIVOROUS BATSThe Journal of Experimental Medicine, 110
A. Botvinkin, E. Poleschuk, I. Kuzmin, T. Borisova, S. Gazaryan, P. Yager, C. Rupprecht (2003)
Novel Lyssaviruses Isolated from Bats in RussiaEmerging Infectious Diseases, 9
G. Baer, G. Bales (1967)
Experimental rabies infection in the Mexican freetail bat.The Journal of infectious diseases, 117 1
I. Kuzmin, L. Orciari, Y. Arai, Jean Smith, C. Hanlon, Y. Kameoka, C. Rupprecht (2003)
Bat lyssaviruses (Aravan and Khujand) from Central Asia: phylogenetic relationships according to N, P and G gene sequences.Virus research, 97 2
J. Moreno, G. Baer (1980)
Experimental rabies in the vampire bat.The American journal of tropical medicine and hygiene, 29 2
V. Shankar, R. Bowen, April Davis, C. Rupprecht, T. O'Shea (2004)
RABIES IN A CAPTIVE COLONY OF BIG BROWN BATS (EPTESICUS FUSCUS), 40
(1992)
Experimental inoculation of bats with lyssaviruses serotypes 1 and 4
H. Bourhy, B. Kissi, Monique Lafon, D. Sacramento, Noël Tordo (1992)
Antigenic and molecular characterization of bat rabies virus in EuropeJournal of Clinical Microbiology, 30
S. Hogenhout, M. Redinbaugh, E. Ammar (2003)
Plant and animal rhabdovirus host range: a bug's view.Trends in microbiology, 11 6
(1991)
Rabies in nonhematophagous bats. In: Baer GM (ed) The natural history of rabies, 2nd edn
(1967)
Rabies transmission by air in bat caves
J. Serra-Cobo, B. Amengual, C. Abellan, H. Bourhy (2002)
European Bat Lyssavirus Infection in Spanish Bat PopulationsEmerging Infectious Diseases, 8
F. Meslin, M. Kaplan, H. Forrner
Laboratory Techniques in Rabies
G. Baer (1978)
The natural history of rabiesMedical History, 22
J. Echevarría, A. Avellón, J. Juste, M. Vera, C. Ibáñez (2001)
Screening of Active Lyssavirus Infection in Wild Bat Populations by Viral RNA Detection on Oropharyngeal SwabsJournal of Clinical Microbiology, 39
S. Nadin-Davis, Wei Huang, J. Armstrong, G. Casey, C. Bahloul, N. Tordo, A. Wandeler (2001)
Antigenic and genetic divergence of rabies viruses from bat species indigenous to Canada.Virus research, 74 1-2
(1994)
Mutation rates and rapid evolution of RNA viruses. In: Morse SS (ed) The evolutionary biology of viruses. raven press, New York, pp 161–184 Experimental lyssavirus infection of bats
G. Wellenberg, L. Audry, L. Rønsholt, W. Poel, C. Bruschke, H. Bourhy (2002)
Presence of European bat lyssavirus RNAs in apparently healthy Rousettus aegyptiacus batsArchives of Virology, 147
AA Setien, B Brochier, N Tordo, O De Paz, P Desmettre, D Peharpre, PP Pastoret (1998)
Experimental rabies infection and oral vaccination in vampire batsVaccine, 16
A. Mondul, J. Krebs, J. Childs (2003)
Trends in national surveillance for rabies among bats in the United States (1993-2000).Journal of the American Veterinary Medical Association, 222 5
Here we describe the results of experimental infections of captive big brown bats ( Eptesicus fuscus ) with three newly isolated bat lyssaviruses from Eurasia (Aravan, Khujand, and Irkut viruses). Infection of E. fuscus was moderate (total, 55–75%). There was no evidence of transmission to in-contact cage mates. Incubation periods for Irkut virus infection were significantly shorter ( p < 0.05) than for either Aravan or Khujand virus infections. In turn, quantification of viral RNA by TaqMan PCR suggests that the dynamics of Irkut virus infection may differ from those of Aravan/Khujand virus infection. Although infectious virus and viral RNA were detected in the brain of every rabid animal, dissemination to non-neuronal tissues was limited. Levels of viral RNA in brain of Aravan/Khujand virus-infected bats was significantly correlated with the number of other tissues positive by TaqMan PCR ( p < 0.05), whereas no such relationship was observed for Irkut virus infection (where viral RNA was consistently detected in all tissues other than kidney). Infectious virus was isolated sporadically from salivary glands, and both infectious virus and viral RNA were obtained from oral swabs. The detection of viral RNA in oral swabs suggests that viral shedding in saliva occurred <5 days before the onset of clinical disease.
Archives of Virology – Springer Journals
Published: Oct 1, 2006
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