Excess of all-cause mortality after a fracture in type 2 diabetic patients: a population-based cohort study

Excess of all-cause mortality after a fracture in type 2 diabetic patients: a population-based... Summary Post-fracture mortality in type 2 diabetes mellitus dently associated with a reduced lifespan, but it is unknown (T2DM) patients has been poorly studied. We report an abso- if T2DM confers an excess post-fracture mortality compared lute and relative excess all-cause mortality following a frac- to non-diabetic fracture patients. We report post-fracture all- ture in these patients compared to non-diabetic patients. cause mortality according to T2DM status. Methods This is a population-based cohort study using da- ta from the SIDIAP database. All ≥50 years old T2DM patients registered in SIDIAP in 2006–2013 and two diabetes-free controls matched on age, gender, and primary Electronic supplementary material The online version of this article care center were selected. Study outcome was all-cause (doi:10.1007/s00198-017-4096-y) contains supplementary material, mortality following incident fractures. Participants were which is available to authorized users. followed from date of any fracture (AF), hip fracture (HF), and clinical vertebral fracture (VF) until the earliest * D. Prieto-Alhambra Daniel.prietoalhambra@ndorms.ox.ac.uk of death or censoring. Cox regression was used to calculate mortality according to T2DM status after adjustment for GREMPAL Research Group, Idiap Jordi Gol Primary Care Research age, gender, body mass index, smoking, alcohol intake, Institute, CIBERFES ISCIII, Universitat Autonoma de Barcelona, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Osteoporosis International Springer Journals

Excess of all-cause mortality after a fracture in type 2 diabetic patients: a population-based cohort study

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Publisher
Springer London
Copyright
Copyright © 2017 by International Osteoporosis Foundation and National Osteoporosis Foundation
Subject
Medicine & Public Health; Orthopedics; Endocrinology; Rheumatology
ISSN
0937-941X
eISSN
1433-2965
D.O.I.
10.1007/s00198-017-4096-y
Publisher site
See Article on Publisher Site

Abstract

Summary Post-fracture mortality in type 2 diabetes mellitus dently associated with a reduced lifespan, but it is unknown (T2DM) patients has been poorly studied. We report an abso- if T2DM confers an excess post-fracture mortality compared lute and relative excess all-cause mortality following a frac- to non-diabetic fracture patients. We report post-fracture all- ture in these patients compared to non-diabetic patients. cause mortality according to T2DM status. Methods This is a population-based cohort study using da- ta from the SIDIAP database. All ≥50 years old T2DM patients registered in SIDIAP in 2006–2013 and two diabetes-free controls matched on age, gender, and primary Electronic supplementary material The online version of this article care center were selected. Study outcome was all-cause (doi:10.1007/s00198-017-4096-y) contains supplementary material, mortality following incident fractures. Participants were which is available to authorized users. followed from date of any fracture (AF), hip fracture (HF), and clinical vertebral fracture (VF) until the earliest * D. Prieto-Alhambra Daniel.prietoalhambra@ndorms.ox.ac.uk of death or censoring. Cox regression was used to calculate mortality according to T2DM status after adjustment for GREMPAL Research Group, Idiap Jordi Gol Primary Care Research age, gender, body mass index, smoking, alcohol intake, Institute, CIBERFES ISCIII, Universitat Autonoma de Barcelona,

Journal

Osteoporosis InternationalSpringer Journals

Published: Jul 25, 2017

References

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