The significance of the spatial organization of chromosomes in germline tissue as a positional system controlling segregation in oogenesis is considered. The history of the problem is reviewed. The author’s data on reorganization of chromosome structure in germline tissue considered in terms of systemic mutations are systematized. The notion of specific morphogenetic field based on chromosome structure, which controls ooplasmic segregation and subsequent developmental stages, is developed.
Russian Journal of Genetics – Springer Journals
Published: Sep 21, 2006
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