Evaluation of the genotoxicity of cadmium in gill cells of the clam Corbicula japonica using the comet assay

Evaluation of the genotoxicity of cadmium in gill cells of the clam Corbicula japonica using the... Cadmium-induced DNA degradation in gill cells of the clam Corbicula japonica was assessed using the comet assay (single-cell gel electrophoresis). Accumulation of highly toxic cadmium in the gill cells of bivalve is accompanied by damage to the cell genome, which is revealed as DNA migration in the comet assay. The main mechanisms of Cd effects on the integrity of the DNA structure are discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Marine Biology Springer Journals

Evaluation of the genotoxicity of cadmium in gill cells of the clam Corbicula japonica using the comet assay

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Publisher
SP MAIK Nauka/Interperiodica
Copyright
Copyright © 2010 by Pleiades Publishing, Ltd.
Subject
Life Sciences; Freshwater & Marine Ecology
ISSN
1063-0740
eISSN
1608-3377
D.O.I.
10.1134/S1063074010040103
Publisher site
See Article on Publisher Site

Abstract

Cadmium-induced DNA degradation in gill cells of the clam Corbicula japonica was assessed using the comet assay (single-cell gel electrophoresis). Accumulation of highly toxic cadmium in the gill cells of bivalve is accompanied by damage to the cell genome, which is revealed as DNA migration in the comet assay. The main mechanisms of Cd effects on the integrity of the DNA structure are discussed.

Journal

Russian Journal of Marine BiologySpringer Journals

Published: Aug 29, 2010

References

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