Cardiovasc Intervent Radiol (2018) 41:1081–1088 https://doi.org/10.1007/s00270-018-1943-y LABORATORY INVESTIGATION Evaluating the Feasibility of Isolated Pancreatic Perfusion for Chemotherapy Using Computed Tomography: An Experimental Study in Pig Models 1 2 3 3 • • • • Satoru Murata Shiro Onozawa Daisuke Yasui Tatsuo Ueda 3 4 5 3 • • • Fumie Sugihara Akira Shimizu Kenichi Suzuki Mitsuo Satake Received: 14 September 2017 / Accepted: 18 March 2018 / Published online: 26 March 2018 Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2018 Abstract to the whole pancreas (%eV) was used to simulate drug Purpose Percutaneous isolated pancreatic perfusion (PIPP) distribution; the result was compared among groups. is performed along with interventional radiology tech- Results Without AMA occlusion, a larger %eV was niques to obtain high drug concentration by occluding the obtained with high infusion rates (P = 0.039). The median arterial inlet and venous outlet of the pancreas. The %eV in Groups 1, 2, and 3 were 57.7, 74.2, and 90.5%, experimental study aimed to evaluate the contrast distri- respectively. With AMA occlusion, CT demonstrated bution in PIPP under different ﬂow rates with or without duodenal enhancement at an infusion
CardioVascular and Interventional Radiology – Springer Journals
Published: Mar 26, 2018
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