Etanercept/infliximab

Etanercept/infliximab Reactions 1704, p157 - 2 Jun 2018 Anal melanoma: case report A 65-year-old man developed anal melanoma following treatment with etanercept and infliximab for rheumatoid arthritis [routes, dosages and durations of treatments to reaction onset not stated]. The man, who had a history of rheumatoid arthritis, presented with rectal bleeding and intermittent anal pain. Examination showed a small, violaceous lesion over the anterior anal verge. Excision of the lesion was performed and pathology revealed a deep and ulcerated malignant melanoma. Subsequently, the man underwent a wide local excision with adequate margins. He reported using etanercept for 15 years and a recent switch to infliximab for rheumatoid arthritis. Infliximab was discontinued upon diagnosis of the melanoma. Author comment: "The risk factors for malignant melanoma are well-established, yet the risk factors for anal melanoma are less clear. In this case, the history of TNF inhibitor use provides a possible risk factor.. . . This link between TNF inhibitor use and the development of melanoma may provide a clue to the etiology of anal melanoma." Kawak S, et al. A diagnosis of cutaneous anal melanoma after long-term TNF inhibitor use. Diseases of the Colon and Rectum 61: e125, No. 5, May 2018. Available from: URL: http://doi.org/10.1097/DCR.0000000000001104 [abstract] - Unknown 803323306 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Etanercept/infliximab

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
Free
1 page
Loading next page...
1 Page
 
/lp/springer_journal/etanercept-infliximab-zCf9oJnkPG
Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46800-8
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p157 - 2 Jun 2018 Anal melanoma: case report A 65-year-old man developed anal melanoma following treatment with etanercept and infliximab for rheumatoid arthritis [routes, dosages and durations of treatments to reaction onset not stated]. The man, who had a history of rheumatoid arthritis, presented with rectal bleeding and intermittent anal pain. Examination showed a small, violaceous lesion over the anterior anal verge. Excision of the lesion was performed and pathology revealed a deep and ulcerated malignant melanoma. Subsequently, the man underwent a wide local excision with adequate margins. He reported using etanercept for 15 years and a recent switch to infliximab for rheumatoid arthritis. Infliximab was discontinued upon diagnosis of the melanoma. Author comment: "The risk factors for malignant melanoma are well-established, yet the risk factors for anal melanoma are less clear. In this case, the history of TNF inhibitor use provides a possible risk factor.. . . This link between TNF inhibitor use and the development of melanoma may provide a clue to the etiology of anal melanoma." Kawak S, et al. A diagnosis of cutaneous anal melanoma after long-term TNF inhibitor use. Diseases of the Colon and Rectum 61: e125, No. 5, May 2018. Available from: URL: http://doi.org/10.1097/DCR.0000000000001104 [abstract] - Unknown 803323306 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off