Estimating Effects of Dynamic Treatment Strategies in Pharmacoepidemiologic Studies with Time-Varying Confounding: a Primer

Estimating Effects of Dynamic Treatment Strategies in Pharmacoepidemiologic Studies with... Curr Epidemiol Rep (2017) 4:288–297 https://doi.org/10.1007/s40471-017-0124-x PHARMACOEPIDEMIOLOGY (S TOH, SECTION EDITOR) Estimating Effects of Dynamic Treatment Strategies in Pharmacoepidemiologic Studies with Time-Varying Confounding: a Primer 1 1 1 Xiaojuan Li & Jessica G. Young & Sengwee Toh Published online: 17 October 2017 Springer International Publishing AG 2017 Abstract the relatively complex analysis. These barriers may be over- Purpose of Review Pharmacoepidemiologists are often inter- come with the increasing availability of data sources contain- ested in estimating the effects of dynamic treatment strategies, ing more detailed time-varying information and more acces- where treatments are modified based on patients’ evolving sible learning tools and software. characteristics. For such problems, appropriate control of both Summary With appropriate data and study design, g-methods baseline and time-varying confounders is critical. can improve our ability to make causal inferences on dynamic Conventional methods that control confounding by including treatment strategies from observational data in pharma time-varying treatments and confounders in an outcome re- coepidemiology. gression model may not have a causal interpretation, even . . when all baseline and time-varying confounders are mea- Keywords Time-varying confounding G-methods . . sured. This problem occurs when time-varying confounders Pharmacoepidemiology Causal inference Dynamic are, themselves, affected by past http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Epidemiology Reports Springer Journals

Estimating Effects of Dynamic Treatment Strategies in Pharmacoepidemiologic Studies with Time-Varying Confounding: a Primer

Loading next page...
 
/lp/springer_journal/estimating-effects-of-dynamic-treatment-strategies-in-QClaZ72KhO
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG
Subject
Medicine & Public Health; Epidemiology
eISSN
2196-2995
D.O.I.
10.1007/s40471-017-0124-x
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial