PharmacoEconomics & Outcomes News 784, p16 - 12 Aug 2017 Estimated costs of ADEs vary with methodology used Estimated costs of adverse drug events (ADEs) in adults in Sweden vary with the methodology used, according to findings of study published in Value in Health. ADEs identified from medical records in a random sample of 4970 Swedish adults over a 3-month period in 2008 were assessed for causality, and their costs were estimated using five evaluation methods: diagnostic code method, main diagnosis method, proportion of registered costs method, resource use method, and unit cost method. Maximum estimated direct healthcare costs due to ADEs ranged from €1538 using the diagnostic code method to €413 770 using the unit cost method. However, the cost per patient ranged from €0 to €500 using the diagnostic code method and unit cost method, respectively, under the most conservative definitions for ADE-related healthcare resource use and causality. "The estimated costs for ADEs were highly affected by the choice of the costing methods, and by applying different thresholds for the uncertainty of a causal connection between the drug and the suspected ADE (step 1 of the cost evaluation) as well as between the ADE and the use of health care resources (step 2). In particular, costing methods based on manual assessment of resource use due to ADEs resulted in higher cost estimates than did methods based on registered diagnoses," said the authors. * 2016 euros Gyllensten H, et al. Comparing Methods for Estimating Direct Costs of Adverse Drug Events. Value in Health : 25 Jul 2017. Available from: URL: https:// doi.org/10.1016/j.jval.2017.06.007 803261497 1173-5503/17/0784-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 12 Aug 2017 No. 784
PharmacoEconomics & Outcomes News – Springer Journals
Published: Aug 12, 2017
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