Strahlenther Onkol (2018) 194:185–195 https://doi.org/10.1007/s00066-017-1227-5 REVIEW ARTICLE Essential role of radiation therapy for the treatment of pancreatic cancer Novel study concepts and established treatment recommendations 1 3 3 1,2 Sophie Dobiasch ·NicoleL.Goerig · Rainer Fietkau · Stephanie E. Combs Received: 14 March 2017 / Accepted: 9 October 2017 / Published online: 1 November 2017 © Springer-Verlag GmbH Deutschland 2017 Abstract concepts are new therapeutic approaches for pancreatic can- Background Pancreatic cancer is one of the most aggressive cer in a multimodal setting with tolerable side effects. Sev- human tumors and the incidence has increased over the last eral clinical studies together with experimental approaches 6 years. In the majority of cases the disease is already in are in process, to deliver further evidence and ultimately an advanced stage at the time of diagnosis where surgery, allow true personalized medicine. the only curative treatment, is no longer an option and ex- plains the still abysmal overall survival. The role of radi- Keywords Intensity modulated radiotherapy · Disease- ation therapy as treatment option for patients with pancre- free survival · Stereotactic radiosurgery · Clinical studies · atic cancer is controversially discussed although radiation Interdisciplinary treatment oncology has emerged as a central
Strahlentherapie und Onkologie – Springer Journals
Published: Nov 1, 2017
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