Epithelioid sarcoma (clinicopathological findings in six cases)

Epithelioid sarcoma (clinicopathological findings in six cases) Epithelioid sarcoma is a soft tissue sarcoma of unknown histogenesis with a predilection of young adults and hand/forearm location. The tumour is often multi-nodular showing central necrosis. Epithelioid cells with large, eosinophilic cytoplasm and spindle cells are characteristic. Epithelial antigens and vimentin are always positive. Tumoural cells show staining for CD34 in 60 to 70% of the cases. The tumour has a high potential of local recurrence and metastasis. Six cases of epithelioid sarcoma were presented. Differential diagnosis and prognosis were emphasized, one patient was female and the mean age was 30. Tumour locations were finger, hand or forearm. All tumours were treated primarily by local excision, five patients had recurrences in a period of 2 to 24 months and three patients died with distant metastasis. Epithelioid sarcoma is a malignant tumour with a high rate of recurrence and metastasis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Epithelioid sarcoma (clinicopathological findings in six cases)

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Publisher
Springer Journals
Copyright
Copyright © 2004 by Springer-Verlag
Subject
Medicine
ISSN
0930-343X
eISSN
1435-0130
D.O.I.
10.1007/s00238-004-0603-4
Publisher site
See Article on Publisher Site

Abstract

Epithelioid sarcoma is a soft tissue sarcoma of unknown histogenesis with a predilection of young adults and hand/forearm location. The tumour is often multi-nodular showing central necrosis. Epithelioid cells with large, eosinophilic cytoplasm and spindle cells are characteristic. Epithelial antigens and vimentin are always positive. Tumoural cells show staining for CD34 in 60 to 70% of the cases. The tumour has a high potential of local recurrence and metastasis. Six cases of epithelioid sarcoma were presented. Differential diagnosis and prognosis were emphasized, one patient was female and the mean age was 30. Tumour locations were finger, hand or forearm. All tumours were treated primarily by local excision, five patients had recurrences in a period of 2 to 24 months and three patients died with distant metastasis. Epithelioid sarcoma is a malignant tumour with a high rate of recurrence and metastasis.

Journal

European Journal of Plastic SurgerySpringer Journals

Published: Apr 1, 2004

References

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