Epirubicin/ifosfamide Reactions 1680, p128 - 2 Dec 2017 Marrow suppression and mucosal ulceration: case report A 29-year-old woman developed marrow suppression and mucosal ulceration during treatment with epirubicin and ifosfamide. The woman was scheduled to receive four cycles of adjuvant chemotherapy with ifosfamide and epirubicin [routes and dosages not stated] for pancreatic liposarcoma. The first cycle of the chemotherapy was initiated in July 2015. However, she developed severe chemotherapy associated adverse reactions (ADRs) such as mucosal ulceration and marrow suppression [duration of treatments to reactions onset and outcomes not stated]. The ADRs resulted in unwillingness to continue the medications. But, the woman decline to change her first-line chemotherapeutic treatment. She later had recurrence of liposarcoma and the chemotherapy was switched to apatinib. Author comment: ’’[T]he patient experienced severe chemotherapy related adverse reactions such as marrow suppression and mucosal ulceration, which resulted the hesitation of the medication use.’’ Han T, et al. Successful treatment of advanced pancreatic liposarcoma with apatinib: A case report and literature review. Cancer Biology and Therapy 18: 635-639, No. 9, 2017. Available from: URL: http:// doi.org/10.1080/15384047.2017.1345394 - China 803285409 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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