Epidemiology and etiological characteristics of hand, foot and mouth disease in Huizhou City between 2008 and 2011

Epidemiology and etiological characteristics of hand, foot and mouth disease in Huizhou City... To study epidemiological features and etiological characteristics of hand, foot and mouth disease (HFMD), 42,012 cases were investigated from April 2008 to December 2011 in Huizhou, China. The average incidence rate was 21.16 per 10,000. The highest peak of HFMD incidence was detected between April and July each year, accounting for 55.93 % of all reported cases; another peak occurred in October through December, accounting for 24.17 % of the cases. Of the reported cases, 89.75 % were in children less than 4 years old, and there was a slight predominance of HFMD in boys and children living in rural and suburban areas. The major pathogens causing HFMD were enterovirus 71 (EV71) and coxsackievirus A16 (CA16). C4a was the most prominent EV71 subgenotype circulating in Huizhou. This founding provides insight for developing public-health interventions for the control and prevention of HFMD, especially for reducing the risk of HFMD in high-risk individuals by taking precautions against enterovirus infections. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Epidemiology and etiological characteristics of hand, foot and mouth disease in Huizhou City between 2008 and 2011

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Publisher
Springer Journals
Copyright
Copyright © 2013 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-012-1566-6
Publisher site
See Article on Publisher Site

Abstract

To study epidemiological features and etiological characteristics of hand, foot and mouth disease (HFMD), 42,012 cases were investigated from April 2008 to December 2011 in Huizhou, China. The average incidence rate was 21.16 per 10,000. The highest peak of HFMD incidence was detected between April and July each year, accounting for 55.93 % of all reported cases; another peak occurred in October through December, accounting for 24.17 % of the cases. Of the reported cases, 89.75 % were in children less than 4 years old, and there was a slight predominance of HFMD in boys and children living in rural and suburban areas. The major pathogens causing HFMD were enterovirus 71 (EV71) and coxsackievirus A16 (CA16). C4a was the most prominent EV71 subgenotype circulating in Huizhou. This founding provides insight for developing public-health interventions for the control and prevention of HFMD, especially for reducing the risk of HFMD in high-risk individuals by taking precautions against enterovirus infections.

Journal

Archives of VirologySpringer Journals

Published: Apr 1, 2013

References

  • Genetic evolution of enterovirus 71: epidemiological and pathological implications
    Bible, JM; Pantelidis, P; Chan, PK
  • Specific detection of enterovirus 71 directly from clinical specimens using real-time RT PCR hybridization probe assay
    Tan, EL; Chow, VT; Kumarasinghe, G

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