Purpose of the review Enterococci are emerging threatening multidrug-resistant bacteria. Enterococcus faecium is a common pathogen associated with severe hospital-acquired infections. The goal of this report is to analyze the evolution of this nosocomial pathogen and study the state of adequate infection control measures. Recent findings Evolution over millions of years has allowed enterococci to develop into a persistent hospital pathogen, an environment where it thrives. Vancomycin-resistant enterococci (VRE) continues to obtain antibiotic resistance elements. Enterococci assem- ble multiple virulence factors. VRE intestinal colonization can promote nosocomial infec- tions. New rapid PCR laboratory tests with high sensitivity and specificity allows for screening of Enterococci in asyptomatic carriers. Summary The efficient clonal dissemination of VRE has led to a potential multidrug- resistant bacteria that is a current and future threat to hospitals worldwide. The thera- peutic options are few and decreasing. Healthcare-associated infection (HAI) prevention is critical in our fight against enterococci. 130 Treatment and Prevention of Hospital Infections (D Vilar-Compte, Section Editor) Introduction Enterococci, specifically vancomycin-resistant entero- baumanni, Pseudomonas aeruginosa,and Enterobacter spp., cocci (VRE), are important nosocomial pathogens all of which are dangerous threats . worldwide [1, 2, 3�� , 4, 5� ]. Healthcare-associated in- Enterococcus also possess multiple
Current Treatment Options in Infectious Diseases – Springer Journals
Published: Apr 20, 2018
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