Int Ophthalmol (2018) 38:1211–1217 https://doi.org/10.1007/s10792-017-0584-5 OR IGINAL PAPER Endothelial cell changes after photorefractive keratectomy with graded usage of mitomycin C . . Hamid Gharaee Siamak Zarei-Ghanavati Reza Alizadeh Mojtaba Abrishami Received: 2 September 2016 / Accepted: 5 June 2017 / Published online: 13 June 2017 Springer Science+Business Media B.V. 2017 Abstract size and polymegathism did not signiﬁcantly change. Purpose To compare differences in the endothelial On the other hand, standard deviation (SD) of cell size cells before and after photorefractive keratectomy (P = 0.008), pleomorphism (P = 0.003) and coefﬁ- (PRK) for myopia with refractive error graded mito- cient of variation (CV) (P = 0.016) were signiﬁcantly mycin C (MMC) application. increased. None of these parameters was related to the Methods In a prospective randomized clinical trial, length of MMC application. Corneal thickness forty-eight myopic patients referred to Khatam-al- decreased signiﬁcantly after the operation but it Anbia Eye Hospital, Mashhad, Iran, for PRK. Patients increased 6 months postoperatively compared with were treated with PRK by a Bausch and Lomb the ﬁrst month (P \ 0.001). Technolas 217z excimer laser (Bausch and Lomb, Conclusion MMC application for PRK in myopia Rochester, NY). MMC was applied after PRK 5 s for
International Ophthalmology – Springer Journals
Published: Jun 13, 2017
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