Endogenous ethanol and acetaldehyde in the mechanisms of adaptation of small mammals to northern conditions

Endogenous ethanol and acetaldehyde in the mechanisms of adaptation of small mammals to northern... Study results on the condition of endogenous ethanol—acetaldehyde system in northern red-backed vole (Myodes (=Clethrionomys) rutilus Pallas, 1779), common species of northern latitudes, are presented. Concentrations of endogenous ethanol (EE) and acetaldehyde (EA) in blood, activities of alcohol dehydrogenase in ethanol oxidation reactions (ADHI) and liver acetaldehyde (ADHII) and aldehyde dehydrogenase (ALDH) reduction, and catalytic parameters of these enzymes are determined for winter and summer periods. Changes in ethanol—metabolizing dehydrogenase enzyme system in northern red-backed vole leading to statistically significant (p < 0.01) increase in blood EE and EA concentrations compared to white nonpedigreed laboratory rats without adaptations to cold (especially in winter period) are determined to serve ecoadaptive, antistress functions, comprising one of the systems for regulation of metabolism intensity in small mammals inhabiting extreme northern conditions. Ecological—physiological functions of EE and EA system are increasing the organism’s resistance to the influence of cold temperatures and maintaining thermoregulation even under rapid, considerable environmental temperature drops. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Ecology Springer Journals

Endogenous ethanol and acetaldehyde in the mechanisms of adaptation of small mammals to northern conditions

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Publisher
Pleiades Publishing
Copyright
Copyright © 2017 by Pleiades Publishing, Ltd.
Subject
Life Sciences; Ecology; Environment, general
ISSN
1067-4136
eISSN
1608-3334
D.O.I.
10.1134/S1067413617010088
Publisher site
See Article on Publisher Site

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