Emergence of Candida glabrata in vulvovaginal candidiasis should be attributed to selective pressure or virulence ability?

Emergence of Candida glabrata in vulvovaginal candidiasis should be attributed to selective... Arch Gynecol Obstet (2017) 296:519–526 DOI 10.1007/s00404-017-4465-y GENERAL GYNECOLOGY Emergence of Candida glabrata in vulvovaginal candidiasis should be attributed to selective pressure or virulence ability? 1 2 3 Sandra Sayuri Nakamura‑Vasconcelos  · Adriana Fiorini  · Pamela Delvas Zanni  · 1 1 4 Patrícia de Souza Bonfim‑Mendonça  · Janine Ribeiro Godoy  · Adriana Araújo Almeida‑Apolonio  · 3 1 Marcia Edilaine Lopes Consolaro  · Terezinha Inez Estivalet Svidzinski   Received: 12 June 2017 / Accepted: 12 July 2017 / Published online: 20 July 2017 © Springer-Verlag GmbH Germany 2017 Abstract Conclusion These results allow hypothesizing that C. Purpose Vulvovaginal candidiasis (VVC) is one of glabrata is an emergent agent in VVC probably because the the most frequent female genital disorders and Candida treatment with fluconazole selects this species. But once glabrata is the second most common agent. Current study adhered, yeasts remain on biotic or abiotic surfaces causing was aimed to study the susceptibility to antifungal agents of colonization or VVC symptomatology. C. glabrata isolated from vaginal samples and some viru- lence attributes in order to better understand why this spe- Keywords Candida glabrata · Fluconazole · Drug cies is emerging as the main VVC agents. resistance · Adherence · Biofilm Methods A total of 60 C. glabrata vaginal isolates were included in this study. Firstly they were screened by sus- ceptibility tests to antifungal agents. The http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Gynecology and Obstetrics Springer Journals

Emergence of Candida glabrata in vulvovaginal candidiasis should be attributed to selective pressure or virulence ability?

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Springer Berlin Heidelberg
Copyright © 2017 by Springer-Verlag GmbH Germany
Medicine & Public Health; Gynecology; Obstetrics/Perinatology/Midwifery; Endocrinology; Human Genetics
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