Electron transfer, 151. Decomposition of peroxynitrite as catalyzed by copper(II)

Electron transfer, 151. Decomposition of peroxynitrite as catalyzed by copper(II) The decomposition of peroxynitrite in aqueous solution at pH 9.8–11.1 is catalyzed by copper(II) at the 10–7–10–6 M level. In the presence of added ammonia (0.03 M) or imidazole (0.005 M), reaction rates were as much as 160 times as great as those in copper-free systems. Catalysis was strongly inhibited by glycine, 2,2-bipyridyl, and EDTA. The yield of nitrite from the decomposition, [NO¯2]/[O=NOO¯]taken = 0.26, did not vary significantly with pH or [CuII]. Variation of reaction rates with [H+] and [CuII] is consistent with partition of the catalyst into an acidic form, (cat)HA (pKA 10.2–10.5), a dimer, (catHA)2, and a basic form (cat)A; only the first of these is active. Both transformations are taken to be initiated by CuII-induced homolysis of the O—O bond in peroxynitrite, yielding the reactive intermediate, a species of the type CuIII(OH). The latter may react further with peroxynitrite (ultimately yielding NO¯2 and O2) or with nitrite (yielding NO¯3). It is further suggested that catalytic activity of the type observed requires a substitution-labile CuII(OH2) function. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Electron transfer, 151. Decomposition of peroxynitrite as catalyzed by copper(II)

Loading next page...
 
/lp/springer_journal/electron-transfer-151-decomposition-of-peroxynitrite-as-catalyzed-by-M5ZeFG06OD
Publisher
Brill Academic Publishers
Copyright
Copyright © 2002 by VSP 2002
Subject
Chemistry; Inorganic Chemistry; Physical Chemistry; Catalysis
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1163/15685670260373335
Publisher site
See Article on Publisher Site

Abstract

The decomposition of peroxynitrite in aqueous solution at pH 9.8–11.1 is catalyzed by copper(II) at the 10–7–10–6 M level. In the presence of added ammonia (0.03 M) or imidazole (0.005 M), reaction rates were as much as 160 times as great as those in copper-free systems. Catalysis was strongly inhibited by glycine, 2,2-bipyridyl, and EDTA. The yield of nitrite from the decomposition, [NO¯2]/[O=NOO¯]taken = 0.26, did not vary significantly with pH or [CuII]. Variation of reaction rates with [H+] and [CuII] is consistent with partition of the catalyst into an acidic form, (cat)HA (pKA 10.2–10.5), a dimer, (catHA)2, and a basic form (cat)A; only the first of these is active. Both transformations are taken to be initiated by CuII-induced homolysis of the O—O bond in peroxynitrite, yielding the reactive intermediate, a species of the type CuIII(OH). The latter may react further with peroxynitrite (ultimately yielding NO¯2 and O2) or with nitrite (yielding NO¯3). It is further suggested that catalytic activity of the type observed requires a substitution-labile CuII(OH2) function.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Oct 13, 2004

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off