Efficient, rapid avenue for synthesis of highly substituted piperidines using polystyrene sulfonic acid

Efficient, rapid avenue for synthesis of highly substituted piperidines using polystyrene... Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2649- x) contains supplementary material, which is available to authorized users. & Abhijeet Mulik abhi_mulik1@rediffmail.com PG Department of Chemistry, Balwant College Vita, Sangli, Maharashtra, India Department of Chemistry, Shivaji University, Kolhapur, India 123 730 A. Mulik et al. Keywords Piperidines  Sulfonic acid  Multicomponent Introduction Synthesis of densely functionalized molecules displaying wide array of applications in a single-step and cost-effective manner is the anchor of contemporary organic chemistry. In the last decade, multicomponent reactions (MCR) have perfectly answered these constraints with their merits such as lower cost, shorter reaction times, high atom economy, energy and time saving [1–7]. MCRs have been proclaimed as potent tools for the synthesis of heterocyclic molecules displaying vital applications in various sectors. Piperidine analogues are privileged groups of organic compounds as they constitute many naturally occurring alkaloids, biologically active synthetic molecules and organic fine chemicals [8–10]. Besides these, they are endowed with antihypertensive [11], antibacterial [12], antimalarial [13], anticonvulsant and anti-inflammatory activities [14]. Owing to their vigorous applications, several methods have been reported for their synthesis using catalysts such as BiNO [15], Indium chloride [16], iodine [17], oxalic acid [18] and many more. However, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Efficient, rapid avenue for synthesis of highly substituted piperidines using polystyrene sulfonic acid

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Springer Netherlands
Copyright © 2016 by Springer Science+Business Media Dordrecht
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
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