Efficient atom-economical solvent-free one-pot multicomponent synthesis of 2-amino-4H-benzo[b]pyrans catalyzed by solid base SiO2-OK as a reusable catalyst

Efficient atom-economical solvent-free one-pot multicomponent synthesis of... An efficient one-pot, atom-economical, three-component reaction of aromatic aldehydes, dimedone, and malononitrile was developed, for the first time, using SiO2-OK as an efficient solid base reusable catalyst, producing various substituted 2-amino-4H-benzo[b]pyran derivatives in good to excellent yields, under solvent-free conditions at 80 °C. This synthesis was confirmed to follow the group–assistant–purification chemistry process, which can avoid traditional chromatography and recrystallization purifications. The catalyst is inexpensive and easily obtained, stable and storable, and easily recycled, being reused at least six times without any marked change in its catalytic activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Efficient atom-economical solvent-free one-pot multicomponent synthesis of 2-amino-4H-benzo[b]pyrans catalyzed by solid base SiO2-OK as a reusable catalyst

Loading next page...
 
/lp/springer_journal/efficient-atom-economical-solvent-free-one-pot-multicomponent-t2QOwesqcF
Publisher
Springer Netherlands
Copyright
Copyright © 2013 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-013-1322-x
Publisher site
See Article on Publisher Site

Abstract

An efficient one-pot, atom-economical, three-component reaction of aromatic aldehydes, dimedone, and malononitrile was developed, for the first time, using SiO2-OK as an efficient solid base reusable catalyst, producing various substituted 2-amino-4H-benzo[b]pyran derivatives in good to excellent yields, under solvent-free conditions at 80 °C. This synthesis was confirmed to follow the group–assistant–purification chemistry process, which can avoid traditional chromatography and recrystallization purifications. The catalyst is inexpensive and easily obtained, stable and storable, and easily recycled, being reused at least six times without any marked change in its catalytic activity.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Jun 29, 2013

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from Google Scholar, PubMed
Create lists to organize your research
Export lists, citations
Access to DeepDyve database
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off