Efficacy of chitosan dressing on endoscopic sinus surgery: a systematic review and meta-analysis

Efficacy of chitosan dressing on endoscopic sinus surgery: a systematic review and meta-analysis Chitosan dressing might be promising to promote the recovery following endoscopic sinus surgery (ESS). However, the results remain controversial. We conducted a systematic review and meta-analysis to explore the influence of chitosan dressing on ESS. PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials (RCTs) assessing the effect of chitosan dressing on endoscopic sinus surgery were included. Two investigators independently searched articles, extracted data, and assessed the quality of included studies. The primary outcomes were synechia and hemostasis. Meta-analysis was performed using random-effect model. Four RCTs involving 268 patients were included in the meta-analysis. Overall following ESS, compared with control intervention, chitosan dressing significantly reduced synechia (RR = 0.25; 95% CI 0.13–0.49; P < 0.0001) and promoted hemostasis (RR = 1.70; 95% CI 1.37–2.11; P < 0.00001), but showed no impact on granulations (RR = 1.18; 95% CI 0.72–1.95; P = 0.52), mucosal edema (RR = 0.88; 95% CI 0.60–1.29; P = 0.51), crusting (RR = 0.85; 95% CI 0.48–1.53; P = 0.60), and infection (RR = 0.88; 95% CI 0.51–1.52; P = 0.64). Compared to control intervention, chitosan dressing could significantly decrease edema and improve hemostasis, but had no effect on granulations, mucosal edema, crusting and infection. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Archives of Oto-Rhino-Laryngology Springer Journals

Efficacy of chitosan dressing on endoscopic sinus surgery: a systematic review and meta-analysis

Loading next page...
 
/lp/springer_journal/efficacy-of-chitosan-dressing-on-endoscopic-sinus-surgery-a-systematic-6unxr1zJkf
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Otorhinolaryngology; Neurosurgery; Head and Neck Surgery
ISSN
0937-4477
eISSN
1434-4726
D.O.I.
10.1007/s00405-017-4584-x
Publisher site
See Article on Publisher Site

Abstract

Chitosan dressing might be promising to promote the recovery following endoscopic sinus surgery (ESS). However, the results remain controversial. We conducted a systematic review and meta-analysis to explore the influence of chitosan dressing on ESS. PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials (RCTs) assessing the effect of chitosan dressing on endoscopic sinus surgery were included. Two investigators independently searched articles, extracted data, and assessed the quality of included studies. The primary outcomes were synechia and hemostasis. Meta-analysis was performed using random-effect model. Four RCTs involving 268 patients were included in the meta-analysis. Overall following ESS, compared with control intervention, chitosan dressing significantly reduced synechia (RR = 0.25; 95% CI 0.13–0.49; P < 0.0001) and promoted hemostasis (RR = 1.70; 95% CI 1.37–2.11; P < 0.00001), but showed no impact on granulations (RR = 1.18; 95% CI 0.72–1.95; P = 0.52), mucosal edema (RR = 0.88; 95% CI 0.60–1.29; P = 0.51), crusting (RR = 0.85; 95% CI 0.48–1.53; P = 0.60), and infection (RR = 0.88; 95% CI 0.51–1.52; P = 0.64). Compared to control intervention, chitosan dressing could significantly decrease edema and improve hemostasis, but had no effect on granulations, mucosal edema, crusting and infection.

Journal

European Archives of Oto-Rhino-LaryngologySpringer Journals

Published: Apr 29, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off