Effects of salpingectomy during abdominal hysterectomy on ovarian reserve: a randomized controlled trial

Effects of salpingectomy during abdominal hysterectomy on ovarian reserve: a randomized... Background: The aim of this study was to investigate the effect of salpingectomy on ovarian function by measuring AMH. Methods: This study was a balanced, single-center, double-blind, randomized, controlled trial in Ruin Tan Arash Hospital, Tehran, between May 2013 and November 2014. A total of 30 patients undergoing elective abdominal hysterectomy were randomized into two groups, 15 with salpingectomy and 15 without salpingectomy. The primary objective of this study was to compare mean difference of anti-Mullerian hormone (AMH) between two groups. The secondary outcomes measured were follicle-stimulating hormone (FSH), operative time, and blood loss. Results: Serum AMH levels decreased at 3 months after hysterectomy in all patients (pre AMH 1.32 ± (0.91); post AMH 1.05 ± (0.88), P < 0.001), the salpingectomy group (pre AMH 1.44 ± (0.94); post AMH 1.13 ± (0.86), P < 0.001) , and no salpingectomy group (pre AMH 1.2 ± (0.9); post AMH 0.97 ± (0.92), P <0.001).Therateofdecline of AMH levels after surgery did not differ between the two groups (25% (17–33%) vs. 26% (15–36%), P = 0.23) among the women with salpingectomy versus without salpingectomy, respectively. There was no difference in the mean operative time (mean difference 0.33, 95% CI − 22.21 to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Gynecological Surgery Springer Journals

Effects of salpingectomy during abdominal hysterectomy on ovarian reserve: a randomized controlled trial

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by The Author(s).
Subject
Medicine & Public Health; Gynecology; Minimally Invasive Surgery; Surgical Oncology; Obstetrics/Perinatology/Midwifery; Reproductive Medicine; Interventional Radiology
ISSN
1613-2076
eISSN
1613-2084
D.O.I.
10.1186/s10397-017-1019-z
Publisher site
See Article on Publisher Site

Abstract

Background: The aim of this study was to investigate the effect of salpingectomy on ovarian function by measuring AMH. Methods: This study was a balanced, single-center, double-blind, randomized, controlled trial in Ruin Tan Arash Hospital, Tehran, between May 2013 and November 2014. A total of 30 patients undergoing elective abdominal hysterectomy were randomized into two groups, 15 with salpingectomy and 15 without salpingectomy. The primary objective of this study was to compare mean difference of anti-Mullerian hormone (AMH) between two groups. The secondary outcomes measured were follicle-stimulating hormone (FSH), operative time, and blood loss. Results: Serum AMH levels decreased at 3 months after hysterectomy in all patients (pre AMH 1.32 ± (0.91); post AMH 1.05 ± (0.88), P < 0.001), the salpingectomy group (pre AMH 1.44 ± (0.94); post AMH 1.13 ± (0.86), P < 0.001) , and no salpingectomy group (pre AMH 1.2 ± (0.9); post AMH 0.97 ± (0.92), P <0.001).Therateofdecline of AMH levels after surgery did not differ between the two groups (25% (17–33%) vs. 26% (15–36%), P = 0.23) among the women with salpingectomy versus without salpingectomy, respectively. There was no difference in the mean operative time (mean difference 0.33, 95% CI − 22.21 to

Journal

Gynecological SurgerySpringer Journals

Published: Aug 17, 2017

References

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