Effects of NO-synthase inhibitors on maturation mouse oocytes in cumulus-oocyte complexes

Effects of NO-synthase inhibitors on maturation mouse oocytes in cumulus-oocyte complexes We studied the effects of various NO-synthase inhibitors on meiotic maturation of mouse oocytes in vitro in cumulus-oocyte complexes isolated from follicles of varying sizes. Selective and nonselective inhibitors of NO-synthase isoforms suppressed meiotic maturation of oocytes to varying degrees, which was expressed in a decreased number of oocytes at metaphase II. The results obtained suggest that the role of inducible form of NO-synthase (iNOS) increases with the development of follicles and oocytes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

Effects of NO-synthase inhibitors on maturation mouse oocytes in cumulus-oocyte complexes

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Publisher
Nauka/Interperiodica
Copyright
Copyright © 2006 by Pleiades Publishing, Inc.
Subject
Life Sciences; Developmental Biology; Animal Anatomy / Morphology / Histology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1134/S1062360406060087
Publisher site
See Article on Publisher Site

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