N-Arachidonoyl dopamine and haloperidol, both separately and in different combinations, inhibit regeneration of the gastral and basal regions of hydra. In addition, both substances induce stable anomalies of morphogenesis in the form of outgrowths and additional tentacles in gastral regenerates. In the presence of both substances at different combinations, anomalies either do not appear altogether, or exist for a short time, thus suggesting the normalization pf morphogenesis. Possible mechanisms underlying the effects of these substances are discussed.
Russian Journal of Developmental Biology – Springer Journals
Published: Dec 30, 2004
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