Effects of enamel matrix derivative on non-surgical management of peri-implant mucositis: a double-blind randomized clinical trial

Effects of enamel matrix derivative on non-surgical management of peri-implant mucositis: a... Clin Oral Invest (2017) 21:2379–2388 DOI 10.1007/s00784-016-2033-7 ORIGINAL ARTICLE Effects of enamel matrix derivative on non-surgical management of peri-implant mucositis: a double-blind randomized clinical trial 1 1,2,3 1 1,4 Atabak Kashefimehr & Reza Pourabbas & Masumeh Faramarzi & Ali Zarandi & 1 2,3 2,3,5 Abouzar Moradi & Howard C. Tenenbaum & Amir Azarpazhooh Received: 2 March 2016 /Accepted: 8 December 2016 /Published online: 30 December 2016 Springer-Verlag Berlin Heidelberg 2016 Abstract The levels of IL-6 and IL-17 cytokines in PICF were evaluat- Background Peri-implant diseases have been recognized as ed by enzyme-linked immunosorbent (ELISA). being among the ever-increasing complications related to den- Results Three-month post-interventional assay revealed sig- tal implants. The aim of this study was to evaluate the adjunc- nificant improvements in BOP and PD in the test group in tive use of enamel matrix derivative (EMD) to mechanical comparison to the control group (P < 0.0001). Relative to debridement (MD) in patients with these conditions in terms control, IL-6 and IL-17 levels were reduced significantly of clinical parameters and cytokine levels of peri-implant cre- (p < 0.05) in the test group compared to the control group. vicular fluid (PICF). Conclusion Application of EMD can be considered an http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Oral Investigations Springer Journals

Effects of enamel matrix derivative on non-surgical management of peri-implant mucositis: a double-blind randomized clinical trial

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2016 by Springer-Verlag Berlin Heidelberg
Subject
Dentistry; Dentistry
ISSN
1432-6981
eISSN
1436-3771
D.O.I.
10.1007/s00784-016-2033-7
Publisher site
See Article on Publisher Site

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