Eur J Nutr (2018) 57:95–106 https://doi.org/10.1007/s00394-016-1300-3 ORIGINAL CONTRIBUTION Effect of probiotics and synbiotics on blood glucose: a systematic review and meta‑analysis of controlled trials 1,2 1,3 1,2 1 Elham Nikbakht · Saman Khalesi · Indu Singh · Lauren Therese Williams · 1 1,2 Nicholas P. West · Natalie Colson Received: 13 December 2015 / Accepted: 16 August 2016 / Published online: 3 September 2016 © Springer-Verlag Berlin Heidelberg 2016 Abstract result of subgroup analysis for baseline FBG level ≥7 mmol/L Purpose High fasting blood glucose (FBG) can lead to showed a reduction in FBG of 0.68 mmol/L (−1.07, −0.29; chronic diseases such as diabetes mellitus, cardiovascular ρ < 0.01), while trials with multiple species of probiotics and kidney diseases. Consuming probiotics or synbiotics showed a more pronounced reduction of 0.31 mmol/L (−0.58, may improve FBG. A systematic review and meta-analysis −0.03; ρ = 0.03) compared to single species trials. of controlled trials was conducted to clarify the effect of Conclusion This meta-analysis suggests that probiotic and probiotic and synbiotic consumption on FBG levels. synbiotic supplementation may be beneficial in lowering Methods PubMed, Scopus, Cochrane Library, and Cumu- FBG in adults with high baseline FBG (≥7 mmol/L) and lative Index
European Journal of Nutrition – Springer Journals
Published: Sep 3, 2016
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