Effect of carboxymethyl cellulose viscosity on the size of turmeric extract nanoparticles

Effect of carboxymethyl cellulose viscosity on the size of turmeric extract nanoparticles The turmeric extract nanoparticles were synthesized by complexation involving modified carboxylmethyl cellulose (MCMC) and calcium ions. The effect of viscosity of carboxylmethyl cellulose (CMC) solution on the particle size of turmeric extract nanoparticle was investigated. Firstly, MCMC viscosity decreases with the increase of H2O2 content (as observed from weight ratio between MCMC and CMC) due to chain scission. The chemical structure of CMC was slightly altered after modification as confirmed by ATR-FTIR and XRD. The parameters affecting the nanoparticle size were investigated using Zetasizer. The resulting nanoparticle size decreased with the increase in the added CaCl2 amount up to the optimal level as observed from dynamic viscosity measurements due to the agglomeration of MCMC chains. Moreover, the nanoparticle size was reduced with increased content of turmeric extract dissolved in ethanol since ethanol is a poor solvent for CMC. However, the nanoparticle size increased with the increase of MCMC concentration due to the growth of MCMC dynamic viscosity. The Zeta potential of nanoparticles reaches the maximum at the lowest CaCl2 concentration. After drying, the aggregation of nanoparticles appeared as observed by SEM and TEM. Finally, the obtained nanoparticles are promising for colon cancer therapy as shown by 98–99% inhibition of colon cancer in the performed tests. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Applied Chemistry Springer Journals

Effect of carboxymethyl cellulose viscosity on the size of turmeric extract nanoparticles

Loading next page...
 
/lp/springer_journal/effect-of-carboxymethyl-cellulose-viscosity-on-the-size-of-turmeric-aZ0wbnqlxp
Publisher
Pleiades Publishing
Copyright
Copyright © 2014 by Pleiades Publishing, Ltd.
Subject
Chemistry; Chemistry/Food Science, general; Industrial Chemistry/Chemical Engineering
ISSN
1070-4272
eISSN
1608-3296
D.O.I.
10.1134/S1070427214100152
Publisher site
See Article on Publisher Site

Abstract

The turmeric extract nanoparticles were synthesized by complexation involving modified carboxylmethyl cellulose (MCMC) and calcium ions. The effect of viscosity of carboxylmethyl cellulose (CMC) solution on the particle size of turmeric extract nanoparticle was investigated. Firstly, MCMC viscosity decreases with the increase of H2O2 content (as observed from weight ratio between MCMC and CMC) due to chain scission. The chemical structure of CMC was slightly altered after modification as confirmed by ATR-FTIR and XRD. The parameters affecting the nanoparticle size were investigated using Zetasizer. The resulting nanoparticle size decreased with the increase in the added CaCl2 amount up to the optimal level as observed from dynamic viscosity measurements due to the agglomeration of MCMC chains. Moreover, the nanoparticle size was reduced with increased content of turmeric extract dissolved in ethanol since ethanol is a poor solvent for CMC. However, the nanoparticle size increased with the increase of MCMC concentration due to the growth of MCMC dynamic viscosity. The Zeta potential of nanoparticles reaches the maximum at the lowest CaCl2 concentration. After drying, the aggregation of nanoparticles appeared as observed by SEM and TEM. Finally, the obtained nanoparticles are promising for colon cancer therapy as shown by 98–99% inhibition of colon cancer in the performed tests.

Journal

Russian Journal of Applied ChemistrySpringer Journals

Published: Jan 23, 2015

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off