Econazole/triamcinolone

Econazole/triamcinolone Reactions 1704, p150 - 2 Jun 2018 Drug allergy resulting in worsening of seborrhoeic dermatitis: case report A 13-year-old girl developed drug allergy that further resulted in worsening of underlying seborrhoeic dermatitis during treatment with topical triamcinolone [triamcinolone- acetonide] and topical econazole [econazole nitrate; dosage not stated]. In March 2015, the girl presented to an outpatient clinic with rash like appearance on both her cheeks along with slight itching. She had fungal infection and was diagnosed with seborrhoeic dermatitis. She was prescribed topical 1% econazole and 0.1% triamcinolone cream along with oral itraconazole. However, several hours following the first application of the topical triamcinolone and econazole, she developed a strong reaction to the topical agents [time to reaction onset not clearly stated]. Her lesions became more reddish, worsened and enlarged. Oozing and swelling with severe burning sensation and itching was also noted. The girl’s parents allowed her to stop using both the topical and oral treatments. Consequently, the lesions stopped worsening. The following day, she presented to a different clinic where the treatment of her underlying seborrhoeic dermatitis was initiated with traditional Chinese medications. Improvement was noted in her condition after a week of treatment. By the fifth week of treatment, her condition resolved completely and during follow up visit at six months, recurrence of seborrhoeic dermatitis was not noted. Author comment: "This paper reports the case of a 13-year-old girl with facial seborrhoeic dermatitis (combined with fungal infection), who was allergic to conventional topical agents and was cured successfully with Chinese herbal medicine." "In this patient, topical corticosteroid and an anti- fungal agent were used as first-line medical treatments, but allergic reaction to the ointment exacerbated the lesion." Xiao M, et al. Chinese herbal medicine for seborrheic dermatitis complicated by allergy to topical agent: A case report. Journal of Traditional Chinese Medical Sciences 4: 380-383, No. 4, Oct 2017. Available from: URL: http:// doi.org/10.1016/j.jtcms.2017.12.004 - China 803322998 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Econazole/triamcinolone

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46793-1
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p150 - 2 Jun 2018 Drug allergy resulting in worsening of seborrhoeic dermatitis: case report A 13-year-old girl developed drug allergy that further resulted in worsening of underlying seborrhoeic dermatitis during treatment with topical triamcinolone [triamcinolone- acetonide] and topical econazole [econazole nitrate; dosage not stated]. In March 2015, the girl presented to an outpatient clinic with rash like appearance on both her cheeks along with slight itching. She had fungal infection and was diagnosed with seborrhoeic dermatitis. She was prescribed topical 1% econazole and 0.1% triamcinolone cream along with oral itraconazole. However, several hours following the first application of the topical triamcinolone and econazole, she developed a strong reaction to the topical agents [time to reaction onset not clearly stated]. Her lesions became more reddish, worsened and enlarged. Oozing and swelling with severe burning sensation and itching was also noted. The girl’s parents allowed her to stop using both the topical and oral treatments. Consequently, the lesions stopped worsening. The following day, she presented to a different clinic where the treatment of her underlying seborrhoeic dermatitis was initiated with traditional Chinese medications. Improvement was noted in her condition after a week of treatment. By the fifth week of treatment, her condition resolved completely and during follow up visit at six months, recurrence of seborrhoeic dermatitis was not noted. Author comment: "This paper reports the case of a 13-year-old girl with facial seborrhoeic dermatitis (combined with fungal infection), who was allergic to conventional topical agents and was cured successfully with Chinese herbal medicine." "In this patient, topical corticosteroid and an anti- fungal agent were used as first-line medical treatments, but allergic reaction to the ointment exacerbated the lesion." Xiao M, et al. Chinese herbal medicine for seborrheic dermatitis complicated by allergy to topical agent: A case report. Journal of Traditional Chinese Medical Sciences 4: 380-383, No. 4, Oct 2017. Available from: URL: http:// doi.org/10.1016/j.jtcms.2017.12.004 - China 803322998 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

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