Early diagnosis and treatment of steroid-induced osteonecrosis of the femoral head

Early diagnosis and treatment of steroid-induced osteonecrosis of the femoral head Objective This study aims to investigate the early diagnosis and treatment of steroid-induced osteonecrosis of the femoral head. Patients and methods From January 2010 to January 2014, a total of 350 patients, who required the use of large amounts of hormones, were enrolled into the study. These patients were followed up every three months after starting the hormone therapy. A total of 62 cases were screened, among which nine cases were asymptomatic. Furthermore, 38 patients were diagnosed as stage I and were given low-molecular weight heparin (LMWH) and vasodilator drugs. Moreover, 22 cases were diagnosed as stage IIa/b and underwent core decompression. In addition, two cases were diagnosed as stage IIc and underwent pedicled bone transplan- tation. During the follow-up period, ARCO staging was used for radiological evaluation, the HHS score was applied to evaluate for clinical efficacy, and SPSS 22.0 statistical software was used for the data analysis. Results A total of 60 patients were followed up for 24 months. Among these patients, 38 patients were diagnosed with ARCO stage I and underwent systematic therapy. No progress was found in 29 cases (76.3%). Furthermore, three cases progressed to stage IIb (7.8%), four cases progressed to stage IIc (10.5%), http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Orthopaedics Springer Journals

Early diagnosis and treatment of steroid-induced osteonecrosis of the femoral head

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Publisher
Springer Journals
Copyright
Copyright © 2018 by SICOT aisbl
Subject
Medicine & Public Health; Orthopedics
ISSN
0341-2695
eISSN
1432-5195
D.O.I.
10.1007/s00264-018-4011-y
Publisher site
See Article on Publisher Site

Abstract

Objective This study aims to investigate the early diagnosis and treatment of steroid-induced osteonecrosis of the femoral head. Patients and methods From January 2010 to January 2014, a total of 350 patients, who required the use of large amounts of hormones, were enrolled into the study. These patients were followed up every three months after starting the hormone therapy. A total of 62 cases were screened, among which nine cases were asymptomatic. Furthermore, 38 patients were diagnosed as stage I and were given low-molecular weight heparin (LMWH) and vasodilator drugs. Moreover, 22 cases were diagnosed as stage IIa/b and underwent core decompression. In addition, two cases were diagnosed as stage IIc and underwent pedicled bone transplan- tation. During the follow-up period, ARCO staging was used for radiological evaluation, the HHS score was applied to evaluate for clinical efficacy, and SPSS 22.0 statistical software was used for the data analysis. Results A total of 60 patients were followed up for 24 months. Among these patients, 38 patients were diagnosed with ARCO stage I and underwent systematic therapy. No progress was found in 29 cases (76.3%). Furthermore, three cases progressed to stage IIb (7.8%), four cases progressed to stage IIc (10.5%),

Journal

International OrthopaedicsSpringer Journals

Published: Jun 6, 2018

References

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