Reactions 1704, p148 - 2 Jun 2018 Iatrogenic engorgement of the clitoris: case report A 39-year-old woman developed iatrogenic engorgement of the clitoris during treatment with escitalopram, duloxetine and venlafaxine for adjustment disorder with depressed mood [routes not stated]. The woman, who had an adjustment disorder with depressed mood, started receiving treatment with escitalopram 20mg per day. After two days of the therapy, she developed occasional burning, swelling of the clitoris and pinpricks. In a few days, the symptoms turned stronger and regular. An adverse reaction to escitalopram was considered. The woman’s escitalopram was discontinued, and she recovered completely after a week. Thereafter, she was started on duloxetine 30mg per day. However, after two days of the therapy, she experienced the similar symptoms as occurred previously. After a week, duloxetine was stopped with immediate improvement in the symptoms and complete resolution after a few days. At the age of 41 years, she experienced another episode of adjustment disorder with depressed mood and started receiving treatment with venlafaxine 75mg per day. After two days of venlafaxine treatment, she again developed burning, swelling of the clitoris and pinprick as occurred previously. Physical examination demonstrated no erection of the clitoris. Venlafaxine was subsequently stopped. Discontinuation of venlafaxine resulted in complete resolution of the symptoms in a week. Author comment: "[E]scitalopram (20 mg) a day was started. After 2 days, she complained of occasional burning, pinpricks, and swelling of the clitoris. . .Suspecting an adverse reaction,the escitalopram was discontinued. . .trial with 30 mg a day of duloxetine caused the appearance of the same symptoms. . .75 mg a day of venlafaxine was started. Similarly to the previous occasion, after 2 days, the patient complained of burning, pinpricks, and swelling of the clitoris." Raudino F, et al. Iatrogenic Engorgement of the Clitoris Due to Antidepressants: Report of a Case. Journal of Clinical Psychopharmacology 38: 280-281, No. 3, Jun 2018. Available from: URL: http://doi.org/10.1097/JCP.0000000000000881 - Italy 803323722 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera