Dual isotope and multidetector camera: The best choices for a specific end-point

Dual isotope and multidetector camera: The best choices for a specific end-point EDITORIAL Dual isotope and multidetector camera: The best choices for a specific end-point a a,b Roberta Assante, MD, and Wanda Acampa, MD, PhD Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy Received Apr 12, 2016; accepted Apr 12, 2016 doi:10.1007/s12350-016-0520-5 of viable but sympathetically denervated myocardial See related article, pp. 1361–1369 areas, defined as trigger zone. In fact, myocardial 123I- MIBG uptake was not only reduced in the central infarct zone involved by the severe reduction of perfusion tra- cer uptake, but also in adjacent still viable regions as Assessment of myocardial infarct tissue has shown well as in areas with acute and chronic ischemia to play an important role in risk-stratify patients for reflecting better the total extent of injured myocardium. adverse cardiac events. Infarct tissue may show con- These regions with impaired innervation may be viable siderable spatial heterogeneity due to the presence of and hypersensitive to catecholamine, resulting in necrotic areas that are intermingled with bundles of increased automaticity and enhanced triggering and it viable cardiomyocytes. Myocardial necrosis is primarily has been demonstrated that the presence of trigger zone located in the middle http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Nuclear Cardiology Springer Journals

Dual isotope and multidetector camera: The best choices for a specific end-point

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Publisher
Springer US
Copyright
Copyright © 2016 by American Society of Nuclear Cardiology
Subject
Medicine & Public Health; Cardiology; Nuclear Medicine; Imaging / Radiology
ISSN
1071-3581
eISSN
1532-6551
D.O.I.
10.1007/s12350-016-0520-5
Publisher site
See Article on Publisher Site

Abstract

EDITORIAL Dual isotope and multidetector camera: The best choices for a specific end-point a a,b Roberta Assante, MD, and Wanda Acampa, MD, PhD Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy Received Apr 12, 2016; accepted Apr 12, 2016 doi:10.1007/s12350-016-0520-5 of viable but sympathetically denervated myocardial See related article, pp. 1361–1369 areas, defined as trigger zone. In fact, myocardial 123I- MIBG uptake was not only reduced in the central infarct zone involved by the severe reduction of perfusion tra- cer uptake, but also in adjacent still viable regions as Assessment of myocardial infarct tissue has shown well as in areas with acute and chronic ischemia to play an important role in risk-stratify patients for reflecting better the total extent of injured myocardium. adverse cardiac events. Infarct tissue may show con- These regions with impaired innervation may be viable siderable spatial heterogeneity due to the presence of and hypersensitive to catecholamine, resulting in necrotic areas that are intermingled with bundles of increased automaticity and enhanced triggering and it viable cardiomyocytes. Myocardial necrosis is primarily has been demonstrated that the presence of trigger zone located in the middle

Journal

Journal of Nuclear CardiologySpringer Journals

Published: May 19, 2016

References

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