Doxorubicin

Doxorubicin Reactions 1680, p123 - 2 Dec 2017 Moderate impairment of cardiac contractibility: case report In a single institution long-term prospective study, a patient [age and sex not stated] was described, who developed moderate impairment of cardiac contractibility during treatment with doxorubicin [duration of treatment to reaction onset not stated]. The patient, who was newly diagnosed with Hodgkin lymphoma, started receiving chemotherapy with ABVD regimen that included IV doxorubicin 25 mg/m for days 1 and 15. Subsequently, the patient developed moderate impairment of cardiac contractibility. The patient was treated with carvedilol and a favourable outcome was achieved. Author comment: "The cumulative dose of doxorubicin raises concern on cardiac contractility in the long term, but if [radiotherapy] is avoided the potentiation of this late effect is reduced." "Other incidental complications were . . .moderate impairment of cardiac contractibility (1 patient treated with carvedilol with favorable outcome)". Zubizarreta PA, et al. Children and Adolescent Hodgkin Lymphoma in Argentina: Long-term Results After Combined ABVD and Restricted Radiotherapy. Journal of Pediatric Hematology/Oncology 39: 602-608, No. 8, Nov 2017. Available from: URL: http://doi.org/10.1097/MPH.0000000000000943 - Argentina 803285521 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Doxorubicin

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
Free
1 page

Loading next page...
1 Page
 
/lp/springer_journal/doxorubicin-iqrtuLkBM7
Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-39054-6
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p123 - 2 Dec 2017 Moderate impairment of cardiac contractibility: case report In a single institution long-term prospective study, a patient [age and sex not stated] was described, who developed moderate impairment of cardiac contractibility during treatment with doxorubicin [duration of treatment to reaction onset not stated]. The patient, who was newly diagnosed with Hodgkin lymphoma, started receiving chemotherapy with ABVD regimen that included IV doxorubicin 25 mg/m for days 1 and 15. Subsequently, the patient developed moderate impairment of cardiac contractibility. The patient was treated with carvedilol and a favourable outcome was achieved. Author comment: "The cumulative dose of doxorubicin raises concern on cardiac contractility in the long term, but if [radiotherapy] is avoided the potentiation of this late effect is reduced." "Other incidental complications were . . .moderate impairment of cardiac contractibility (1 patient treated with carvedilol with favorable outcome)". Zubizarreta PA, et al. Children and Adolescent Hodgkin Lymphoma in Argentina: Long-term Results After Combined ABVD and Restricted Radiotherapy. Journal of Pediatric Hematology/Oncology 39: 602-608, No. 8, Nov 2017. Available from: URL: http://doi.org/10.1097/MPH.0000000000000943 - Argentina 803285521 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off