Donor derived T-cell large granular lymphocyte leukemia after cord blood transplant for pediatric T-cell lymphoblastic leukemia

Donor derived T-cell large granular lymphocyte leukemia after cord blood transplant for pediatric... Bone Marrow Transplantation (2018) 53:352–355 https://doi.org/10.1038/s41409-017-0037-9 CORRESPONDENCE Donor derived T-cell large granular lymphocyte leukemia after cord blood transplant for pediatric T-cell lymphoblastic leukemia 1 2 2 2 3 2 ● ● ● ● ● ● Tyler G. Ketterl David Wu Jonathan R. Fromm Lorinda Soma Ann E. Dahlberg Brent L. Wood Katherine Tarlock Received: 5 September 2017 / Revised: 29 September 2017 / Accepted: 2 October 2017 / Published online: 21 December 2017 © Macmillan Publishers Limited, part of Springer Nature 2018 Large granular lymphocyte (LGL) leukemia is characterized cyclophosphamide and total body irradiation (13.2 Gy) by a clonal expansion of either CD3(+) cytotoxic T or with cranial boost. Graft versus host disease (GVHD) CD3(−) NK cells. LGL leukemia most commonly affects prophylaxis included cyclosporine and mycophenolate the elderly with a median age of 60, although cases in mofetil. Early post-transplant, the patient developed acute younger adults and very rarely pediatric patients have been skin grade IIB GVHD which was treated with high-dose reported [1–4]. In most cases T-LGL leukemia is associated prednisone. Following completion of an initial prednisone with an indolent clinical course characterized by cytopenias taper, she developed delayed acute gastrointestinal GVHD grade IIA that was treated http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Bone Marrow Transplantation Springer Journals

Donor derived T-cell large granular lymphocyte leukemia after cord blood transplant for pediatric T-cell lymphoblastic leukemia

Loading next page...
 
/lp/springer_journal/donor-derived-t-cell-large-granular-lymphocyte-leukemia-after-cord-TqI9ZnuAuh
Publisher
Nature Publishing Group UK
Copyright
Copyright © 2017 by The Author(s) 2017, under exclusive licence to Macmillan Publishers Limited, part of Springer Nature
Subject
Medicine & Public Health; Medicine/Public Health, general; Internal Medicine; Cell Biology; Public Health; Hematology; Stem Cells
ISSN
0268-3369
eISSN
1476-5365
D.O.I.
10.1038/s41409-017-0037-9
Publisher site
See Article on Publisher Site

Abstract

Bone Marrow Transplantation (2018) 53:352–355 https://doi.org/10.1038/s41409-017-0037-9 CORRESPONDENCE Donor derived T-cell large granular lymphocyte leukemia after cord blood transplant for pediatric T-cell lymphoblastic leukemia 1 2 2 2 3 2 ● ● ● ● ● ● Tyler G. Ketterl David Wu Jonathan R. Fromm Lorinda Soma Ann E. Dahlberg Brent L. Wood Katherine Tarlock Received: 5 September 2017 / Revised: 29 September 2017 / Accepted: 2 October 2017 / Published online: 21 December 2017 © Macmillan Publishers Limited, part of Springer Nature 2018 Large granular lymphocyte (LGL) leukemia is characterized cyclophosphamide and total body irradiation (13.2 Gy) by a clonal expansion of either CD3(+) cytotoxic T or with cranial boost. Graft versus host disease (GVHD) CD3(−) NK cells. LGL leukemia most commonly affects prophylaxis included cyclosporine and mycophenolate the elderly with a median age of 60, although cases in mofetil. Early post-transplant, the patient developed acute younger adults and very rarely pediatric patients have been skin grade IIB GVHD which was treated with high-dose reported [1–4]. In most cases T-LGL leukemia is associated prednisone. Following completion of an initial prednisone with an indolent clinical course characterized by cytopenias taper, she developed delayed acute gastrointestinal GVHD grade IIA that was treated

Journal

Bone Marrow TransplantationSpringer Journals

Published: Dec 21, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from Google Scholar, PubMed
Create lists to organize your research
Export lists, citations
Access to DeepDyve database
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off