DNA diagnosis of peritoneal fluid cytology test by CDO1 promoter DNA hypermethylation in gastric cancer

DNA diagnosis of peritoneal fluid cytology test by CDO1 promoter DNA hypermethylation in gastric... Gastric Cancer (2017) 20:784–792 DOI 10.1007/s10120-017-0697-6 ORIGINAL ARTICLE DNA diagnosis of peritoneal fluid cytology test by CDO1 promoter DNA hypermethylation in gastric cancer 1 1 1 1 • • • • Hideki Ushiku Keishi Yamashita Akira Ema Naoko Minatani 1 1 1 1 • • • • Mariko Kikuchi Ken Kojo Keigo Yokoi Toshimichi Tanaka 1 1 1 1 • • • • Nobuyuki Nishizawa Satoru Ishii Kei Hosoda Hiromitsu Moriya 1 1 1 1 • • • • Hiroaki Mieno Natsuya Katada Shiro Kikuchi Hiroshi Katoh Masahiko Watanabe Received: 11 December 2016 / Accepted: 20 January 2017 / Published online: 27 February 2017 The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2017 Abstract detect minimal residual disease of the peritoneum in GC Background Minimal residual disease of the peritoneum is clinics as a novel DNA marker. challenging for early cancer detection in gastric cancer (GC). Utility of PCR amplification of cancer-derived DNA Keywords Cysteine dioxygenase type 1 (CDO1)  DNA has been considered feasible due to its molecular stability, methylation  Gastric cancer  Peritoneal fluid cytology however such markers have never been available in GC test  DNA diagnosis clinics. We recently discovered cancer-specific http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Gastric Cancer Springer Journals

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Publisher
Springer Japan
Copyright
Copyright © 2017 by The International Gastric Cancer Association and The Japanese Gastric Cancer Association
Subject
Medicine & Public Health; Surgical Oncology; Oncology; Abdominal Surgery; Gastroenterology; Cancer Research
ISSN
1436-3291
eISSN
1436-3305
D.O.I.
10.1007/s10120-017-0697-6
Publisher site
See Article on Publisher Site

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