Access the full text.
Sign up today, get DeepDyve free for 14 days.
Ying Fang, D. Kim, S. Ropp, Pamela Steen, J. Christopher-Hennings, E. Nelson, R. Rowland (2004)
Heterogeneity in Nsp2 of European-like porcine reproductive and respiratory syndrome viruses isolated in the United States.Virus research, 100 2
SL Ropp, CE Wees, Y Fang, EA Nelson, KD Rossow, M Bien, B Arndt, S Preszler, P Steen, J Christopher-Hennings, JE Collins, DA Benfield, KS Faaberg (2004)
Characterization of emerging European-like PRRSV isolates in the United StatesJ Virol, 78
T. Goldberg, James Lowe, Suzanne Milburn, L. Firkins (2003)
Quasispecies variation of porcine reproductive and respiratory syndrome virus during natural infection.Virology, 317 2
J. Thompson, T. Gibson, F. Plewniak, F. Jeanmougin, D. Higgins (1997)
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.Nucleic acids research, 25 24
S. Ropp, C. Wees, Ying Fang, E. Nelson, K. Rossow, Melissa Bien, Bill Arndt, Sarah Preszler, Pamela Steen, J. Christopher-Hennings, J. Collins, D. Benfield, K. Faaberg (2004)
Characterization of Emerging European-Like Porcine Reproductive and Respiratory Syndrome Virus Isolates in the United StatesJournal of Virology, 78
J. Vugt, T. Storgaard, M. Oleksiewicz, A. Bøtner (2001)
High frequency RNA recombination in porcine reproductive and respiratory syndrome virus occurs preferentially between parental sequences with high similarity.The Journal of general virology, 82 Pt 11
J. Meulenberg, M. Hulst, E. Meijer, P. Moonen, A. Besten, E. Kluyver, G. Wensvoort, R. Moormann (1993)
Lelystad Virus, the Causative Agent of Porcine Epidemic Abortion and Respiratory Syndrome (PEARS), Is Related to LDV and EAVVirology, 192
J. Ziebuhr, E. Snijder, A. Gorbalenya (2000)
Virus-encoded proteinases and proteolytic processing in the Nidovirales.The Journal of general virology, 81 Pt 4
V. Kapur, M. Elam, T. Pawlovich, M. Murtaugh (1996)
Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States.The Journal of general virology, 77 ( Pt 6)
K. Lole, R. Bollinger, R. Paranjape, D. Gadkari, S. Kulkarni, Nicole Novak, Roxann Ingersoll, H. Sheppard, S. Ray (1999)
Full-Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype RecombinationJournal of Virology, 73
(2002)
GenBank submission AF514803
E. Snijder, H. Tol, N. Roos, K. Pedersen (2001)
Non-structural proteins 2 and 3 interact to modify host cell membranes during the formation of the arterivirus replication complex.The Journal of general virology, 82 Pt 5
C. Dewey, G. Charbonneau, S. Carman, A. Hamel, G. Nayar, R. Friendship, K. Eernisse, S. Swenson (2000)
Lelystad-like strain of porcine reproductive and respiratory syndrome virus (PRRSV) identified in Canadian swine.The Canadian veterinary journal = La revue veterinaire canadienne, 41 6
S Shen, J Kwang, W Liu, DX Liu (2002)
Determination of the complete nucleotide sequence of a vaccine strain of porcine reproductive and respiratory syndrome virus and identification of the nsp2 gene with a unique insertionArch Virol, 145
A. Wassenaar, W. Spaan, A. Gorbalenya, E. Snijder (1997)
Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine proteaseJournal of Virology, 71
R. Rowland, M. Steffen, T. Ackerman, D. Benfield (1999)
The evolution of porcine reproductive and respiratory syndrome virus: quasispecies and emergence of a virus subpopulation during infection of pigs with VR-2332.Virology, 259 2
S. Yuan, C. Nelsen, M. Murtaugh, B. Schmitt, K. Faaberg (1999)
Short Communication Recombination between North American strains of porcine reproductive and respiratory syndrome virus
E. Snijder, J. Meulenberg (1998)
The molecular biology of arteriviruses.The Journal of general virology, 79 ( Pt 5)
(1995)
The arterivirus nsp2 protease: an unusual cysteine protease with primary structure similarities to both papain-like and chymotrypsin-like proteases
Sudhir Kumar, K. Tamura, M. Nei (1994)
MEGA: Molecular Evolutionary Genetics Analysis software for microcomputersComputer applications in the biosciences : CABIOS, 10 2
S. Yuan, C. Nelsen, M. Murtaugh, B. Schmitt, K. Faaberg (1999)
Recombination between North American strains of porcine reproductive and respiratory syndrome virusVirus Research, 61
M. Oleksiewicz, A. Bøtner, P. Toft, P. Normann, T. Storgaard (2001)
Epitope Mapping Porcine Reproductive and Respiratory Syndrome Virus by Phage Display: the nsp2 Fragment of the Replicase Polyprotein Contains a Cluster of B-Cell EpitopesJournal of Virology, 75
T. Stadejek, A. Stankevičius, T. Storgaard, M. Oleksiewicz, S. Belák, T. Drew, Z. Pejsak (2002)
Identification of radically different variants of porcine reproductive and respiratory syndrome virus in Eastern Europe: towards a common ancestor for European and American viruses.The Journal of general virology, 83 Pt 8
R. Allende, R. Allende, T. Lewis, Zhiqiang Lu, D. Rock, G. Kutish, A. Ali, A. Doster, F. Osorio (1999)
North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions.The Journal of general virology, 80 ( Pt 2)
C. Nelsen, M. Murtaugh, K. Faaberg (1999)
Porcine Reproductive and Respiratory Syndrome Virus Comparison: Divergent Evolution on Two ContinentsJournal of Virology, 73
R. Forsberg, T. Storgaard, H. Nielsen, M. Oleksiewicz, P. Cordioli, G. Sala, J. Hein, A. Bøtner (2002)
The genetic diversity of European type PRRSV is similar to that of the North American type but is geographically skewed within Europe.Virology, 299 1
European-like Type 1 porcine reproductive and respiratory syndrome virus (PRRSV) isolates, known as North American (NA) Type 1 PRRSV, appeared in United States (U.S.) swine herds in 1999. Their diversity and evolution were studied over a five-year period by constructing phylogenetic trees using nsp2 and ORF5 sequences of 20 NA Type 1 isolates, including the only known isolate from Hawaii. All but two of the isolates possessed the same 51-nt deletion in nsp2, suggesting a clonal origin. Parsimony and distance analysis showed that viruses could be placed into two distinct sub-clades, which were similar for both nsp2 and ORF5. An incongruity between the two trees identified one isolate, 04-41, as the product of recombination. Recombination analysis using SimPlot identified a break point located downstream of the nsp2/3 junction. Results from this study suggest that NA Type 1 PRRSV in the U.S. is a well-established and rapidly evolving group. However, the forces driving genetic diversity and separation are complex and remain to be elucidated.
Archives of Virology – Springer Journals
Published: May 1, 2007
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.