Discrimination and ultrasensitive detection of β 2-agonists using copper nanoclusters as a fluorescent probe

Discrimination and ultrasensitive detection of β 2-agonists using copper nanoclusters as a... The authors describe a rapid method for the determination of 11 β 2-agonists by exploiting the color changes and fluorescence intensity changes of copper nanoclusters coated with bovine serum albumin (BSA-CuNCs). On addition to a solution of the BSA-CuNCs, some β 2-agonists (metaproterenol, terbutaline, dopamine hydrochloride, isoproterenol, fenoterol) cause color transitions to occur, while the others do not cause an effect. In addition, β 2-agonists such as isoxsuprine, ritodrine, ractopamine, metaproterenol, terbutaline, dopamine, isoproterenol and fenoterol quench the fluorescence of the CuNCs (best measured at excitation/emission wavelengths of 325/410 nm), while the others do not quench. By combining the effects on color and fluorescence, one can differentiate the various types of agonists. The possible quenching mechanism is investigated. The strong decrease in fluorescence intensity upon addition of certain β 2-agonists can also be used quantify the concentration of the β 2-agonists. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Microchimica Acta Springer Journals

Discrimination and ultrasensitive detection of β 2-agonists using copper nanoclusters as a fluorescent probe

Loading next page...
Springer Vienna
Copyright © 2017 by Springer-Verlag GmbH Austria
Chemistry; Nanochemistry; Nanotechnology; Characterization and Evaluation of Materials; Analytical Chemistry; Microengineering
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial