Keywords Fatty oil · Amazon oil · Amidation · Heterogeneous catalysis · Aluminum oxide 1 Introduction pharmaceutically active compounds, such anti-carcinogenic , anti-tuberculosis , anti-inflammation [8 ] and activity The amidation of fatty acid is an important reaction for against the Alzheimer disease . synthesis of fatty alkanolamines, these compounds have a This class of amides can be naturally found in restricted variety of commercial applications , are used as ingre- organism and microorganisms . Thisis amides are con- dients for detergents, lubricants , fungicides , cor- sidered a neuromodulatory lipid that belongs to a family of rosion inhibitor, agrochemicals , cosmetic  and as signaling molecules collectively termed endocannabinoids , which activate receptors of the type CB1 or CB2, as palmitoylethanolamide, and oleoylethanolamide, similar * Irlon M. Ferreira to anandamide (Fig. 1), but characterized by saturated or email@example.com monounsaturated acyl chains . Extended author information available on the last page of the article Vol.:(0123456789) 1 3 844 P. H. F. Araújo et al. Fig. 1 Chemical structures of endocannabinoids OH OH Oleoylethanolamide Palmitoylethanolamide Fatty alkanolamines are typically synthesized by use of of the country). Hexane was used as the drag solvent by fatty acid ester with an alkanolamine in the presence of a soxhlet extraction for
Catalysis Letters – Springer Journals
Published: Feb 2, 2018
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