Differentiation of cancerous and inflammatory colorectal perforations using multi-detector computed tomography

Differentiation of cancerous and inflammatory colorectal perforations using multi-detector... maximal mural thickness >1.39 cm and irregular con- Purpose: To determine reliable CT features to distinguish figuration of the thickened bowel wall were the two cancerous from inflammatory colorectal perforations. highly statistically significant CT features that may help Materials and methods: A total of 43 patients with order the difference between the two entities. surgically and pathologically confirmed colorectal per- foration caused by either colorectal cancer (n =27) or an Key words: Colorectal neoplasms—Colitis—Crohn’s inflammatory conditions (n = 16) were identified. Two disease—Diverticulitis—Multi-detector computed radiologists independently assessed the contrast-en- tomography hanced CT features for locations of perforation, mural configurations, soft-tissue alterations, lymphadenopathy, and metastases. Intergroup comparisons for univariate Colorectal perforation is a relatively uncommon but analysis were performed using Fisher’s exact test or chi- serious complication of colorectal cancer. The reported square test for categorical data and Mann–Whitney test incidence of perforation ranges from 3% to 10% [1–3]. for numeric data. Stepwise logistic regression analysis Perforated colorectal cancer is typically associated with was conducted with features that were found significant advanced tumor stage, high operative mortality rate, under the univariate analysis. Interobserver agreement and poor prognosis in disease-free survival [4, 5]. was assessed using intraclass correlation coefficient Moreover, colorectal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Abdominal Radiology Springer Journals

Differentiation of cancerous and inflammatory colorectal perforations using multi-detector computed tomography

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Imaging / Radiology; Gastroenterology; Hepatology
ISSN
2366-004X
eISSN
2366-0058
D.O.I.
10.1007/s00261-017-1134-3
Publisher site
See Article on Publisher Site

Abstract

maximal mural thickness >1.39 cm and irregular con- Purpose: To determine reliable CT features to distinguish figuration of the thickened bowel wall were the two cancerous from inflammatory colorectal perforations. highly statistically significant CT features that may help Materials and methods: A total of 43 patients with order the difference between the two entities. surgically and pathologically confirmed colorectal per- foration caused by either colorectal cancer (n =27) or an Key words: Colorectal neoplasms—Colitis—Crohn’s inflammatory conditions (n = 16) were identified. Two disease—Diverticulitis—Multi-detector computed radiologists independently assessed the contrast-en- tomography hanced CT features for locations of perforation, mural configurations, soft-tissue alterations, lymphadenopathy, and metastases. Intergroup comparisons for univariate Colorectal perforation is a relatively uncommon but analysis were performed using Fisher’s exact test or chi- serious complication of colorectal cancer. The reported square test for categorical data and Mann–Whitney test incidence of perforation ranges from 3% to 10% [1–3]. for numeric data. Stepwise logistic regression analysis Perforated colorectal cancer is typically associated with was conducted with features that were found significant advanced tumor stage, high operative mortality rate, under the univariate analysis. Interobserver agreement and poor prognosis in disease-free survival [4, 5]. was assessed using intraclass correlation coefficient Moreover, colorectal

Journal

Abdominal RadiologySpringer Journals

Published: Apr 11, 2017

References

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