Differentiating the acute phase of gout from the intercritical phase with ultrasound and quantitative shear wave elastography

Differentiating the acute phase of gout from the intercritical phase with ultrasound and... Objectives To evaluate the value of ultrasound (US) in differentiating the acute phase of gout from the intercritical phase, particularly using shear wave elastography (SWE). Methods 57 gout patients were prospectively enrolled and divided into acute phase and intercritical phase groups. The patients underwent US and SWE examinations for the first metatarsophalangeal joints with the same protocol. Maximum synovial thickness was measured. US features were reviewed by two radiologists independently. The maximum (E ) and mean max (E ) elastic moduli of synovium were calculated. Diagnostic performances of US, SWE and combined US and SWE were mean evaluated. Results US findings demonstrated that the colour Doppler flow signal grade in the acute phase was higher than that in the intercritical phase (p = 0.001), whereas no differences were found for B-mode US features between the two groups (all p> 0.05). For SWE, E and E were significantly higher in the intercritical phase than in the acute phase (both p <0.001). Theareas max mean under the receiver operating characteristic curve (AUROCs) were 0.494–0.553 for B-mode US, 0.735 for colour Doppler US (CDUS), 0.887 for E and 0.882 for E . The combination of CDUS and SWE increased the AUROC, sensitivity http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Radiology Springer Journals

Differentiating the acute phase of gout from the intercritical phase with ultrasound and quantitative shear wave elastography

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2018 by European Society of Radiology
Subject
Medicine & Public Health; Imaging / Radiology; Diagnostic Radiology; Interventional Radiology; Neuroradiology; Ultrasound; Internal Medicine
ISSN
0938-7994
eISSN
1432-1084
D.O.I.
10.1007/s00330-018-5529-5
Publisher site
See Article on Publisher Site

Abstract

Objectives To evaluate the value of ultrasound (US) in differentiating the acute phase of gout from the intercritical phase, particularly using shear wave elastography (SWE). Methods 57 gout patients were prospectively enrolled and divided into acute phase and intercritical phase groups. The patients underwent US and SWE examinations for the first metatarsophalangeal joints with the same protocol. Maximum synovial thickness was measured. US features were reviewed by two radiologists independently. The maximum (E ) and mean max (E ) elastic moduli of synovium were calculated. Diagnostic performances of US, SWE and combined US and SWE were mean evaluated. Results US findings demonstrated that the colour Doppler flow signal grade in the acute phase was higher than that in the intercritical phase (p = 0.001), whereas no differences were found for B-mode US features between the two groups (all p> 0.05). For SWE, E and E were significantly higher in the intercritical phase than in the acute phase (both p <0.001). Theareas max mean under the receiver operating characteristic curve (AUROCs) were 0.494–0.553 for B-mode US, 0.735 for colour Doppler US (CDUS), 0.887 for E and 0.882 for E . The combination of CDUS and SWE increased the AUROC, sensitivity

Journal

European RadiologySpringer Journals

Published: Jun 4, 2018

References

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