Differentiating pheochromocytoma from lipid-poor adrenocortical adenoma by CT texture analysis: feasibility study

Differentiating pheochromocytoma from lipid-poor adrenocortical adenoma by CT texture analysis:... analysis—Pheochromocytoma—Adrenocortical Objectives: To investigate the feasibility of using CT adenoma—Feasibility texture analysis (CTTA) to differentiate pheochromocy- toma from lipid-poor adrenocortical adenoma (lp-ACA). Methods: Ninety-eight pheochromocytomas and 66 lp- Adrenal masses are being detected with an increased ACAs were included in this retrospective study. CTTA frequency due to the wider application of cross-sectional was performed on unenhanced and enhanced images. imaging [1]. They are discovered in about 5% of patients Receiver operating characteristic (ROC) analysis was who undergo abdominal computed tomography (CT) performed, and the area under the ROC curve (AUC) examinations [2]. In many patients, a specific diagnosis was calculated for texture parameters that were signif- of the adrenal mass could be achieved based on clinical icantly different for the objective. Diagnostic accuracies symptoms, endocrine function tests, and imaging char- were evaluated using the cutoff values of texture param- acteristics. But in patients with asymptomatic nonfunc- eters with the highest AUCs. tioning adrenal masses, in which case imaging plays a Results: Compared to lp-ACAs, pheochromocytomas crucial role in evaluating those patients, it is still quite had significantly higher mean gray-level intensity difficult to make a proper diagnosis, especially when (Mean), entropy, and mean of positive pixels (MPP), imaging features http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Abdominal Radiology Springer Journals

Differentiating pheochromocytoma from lipid-poor adrenocortical adenoma by CT texture analysis: feasibility study

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Imaging / Radiology; Gastroenterology; Hepatology
ISSN
2366-004X
eISSN
2366-0058
D.O.I.
10.1007/s00261-017-1118-3
Publisher site
See Article on Publisher Site

Abstract

analysis—Pheochromocytoma—Adrenocortical Objectives: To investigate the feasibility of using CT adenoma—Feasibility texture analysis (CTTA) to differentiate pheochromocy- toma from lipid-poor adrenocortical adenoma (lp-ACA). Methods: Ninety-eight pheochromocytomas and 66 lp- Adrenal masses are being detected with an increased ACAs were included in this retrospective study. CTTA frequency due to the wider application of cross-sectional was performed on unenhanced and enhanced images. imaging [1]. They are discovered in about 5% of patients Receiver operating characteristic (ROC) analysis was who undergo abdominal computed tomography (CT) performed, and the area under the ROC curve (AUC) examinations [2]. In many patients, a specific diagnosis was calculated for texture parameters that were signif- of the adrenal mass could be achieved based on clinical icantly different for the objective. Diagnostic accuracies symptoms, endocrine function tests, and imaging char- were evaluated using the cutoff values of texture param- acteristics. But in patients with asymptomatic nonfunc- eters with the highest AUCs. tioning adrenal masses, in which case imaging plays a Results: Compared to lp-ACAs, pheochromocytomas crucial role in evaluating those patients, it is still quite had significantly higher mean gray-level intensity difficult to make a proper diagnosis, especially when (Mean), entropy, and mean of positive pixels (MPP), imaging features

Journal

Abdominal RadiologySpringer Journals

Published: Mar 29, 2017

References

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