We studied properties of lactate dehydrogenase isozymes expressed at different stages of Danio rerioontogenesis. H4-LDH and a minor fraction H3M1are expressed during embryonic development. The muscle isozyme (Н4) appears after the beginning of muscle contractions in the embryo. Н4and М4isozymes isolated from the heart and skeletal muscle of the adult fish, respectively, show significant differences in terms of Michaelis constant (K m) activation energy (AE), and inactivation temperature. H4-LDH isozymes isolated from unfertilized eggs, the skeletal muscle of larvae, and the heart of the adult fish differ inK mand activation energy, as well as in inactivation temperature. We propose that these differences may be associated with a ligand interacting with the H4isozyme at different steps of ontogenesis.
Russian Journal of Developmental Biology – Springer Journals
Published: Oct 9, 2004
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera